The peer-reviewed assessment concluded that the body of evidence reviewed is inadequate to either support or refute the safety of the ICNIRP exposure guidelines.
The unsubtle message, in attempts to prop up the ICNIRP position that cellular mobile phone RF radiation and radiation from other wireless communication devices does not pose a health risk, can hardly be mistaken.
The last article in the series of WHO-commissioned SRs reviewed the effects of RF exposure on cancer in experimental animals [16]. This SR was the only WHO-commissioned SR that did not include an MA; the authors deemed it inappropriate because of methodological differences among the studies, including differences in experimental parameters, exposure characteristics, and different biological models. It included all 52 reported studies with 20 chronic bioassays. The SR included all reported studies to minimize the risk of bias concerns. The certainty of the evidence for an increased risk in gliomas was judged as high. Also, in three chronic bioassays, statistically significant increases in malignant schwannomas were demonstrated as high in the heart of male rats. While this conclusion is in opposition to the interpretations of the ICNIRP, it is consistent with the findings of the National Institutes of Health National Toxicology Program [23], [24] and the Ramazzini Institute [25] and is in support of the earlier WHO [International Agency for Research on Cancer (IARC)] conclusion [22]. Almost immediately after the earlier batch of WHO-commissioned SRs was published, evaluations of the quality of those SRs and MAs and the relevance of their conclusions on biological effects and human safety began to appear in scientific publications [17], [18], [19], [20]. The criticisms encountered by those WHO-commissioned SRs and MAs were serious and severe, including calls for retraction....
The recent ICBE-EMF article [1] critically evaluated the 12 WHO-commissioned SRs on the health effects of RF radiation and identified significant flaws and weaknesses that undermine the SRs’ conclusions regarding RF exposure safety. The ICBE-EMF article listed many examples that illustrate the failings in the WHO SRs’ selection of publications. The extensive involvement of present and past members of the ICNIRP raises serious concerns. All of the WHO-commissioned SRs had at least one ICNIRP member as authors, and some had several members. Across multiple SRs, there are issues in the inclusion and exclusion criteria that often led to the exclusion of relevant, well-conducted studies, while flawed studies were given disproportionate weight, thereby undermining the reliability of the evidence assessments.
Simply put, MAs are inappropriate for the WHO SRs. MAs are generally intended to combine quantitative results from multiple studies to estimate overall effects, but their usefulness depends on methodological consistency, low between-study heterogeneity, sufficient statistical power, and statistical independence of the effect sizes. However, as discussed in the ICBE-EMF article, those criteria were mostly unmet in the WHO SRs on RF health effects.
Almost all of the MAs included in the 11 WHO SRs had methodological weaknesses that compromised the interpretability of results because of the relatively few primary studies available for each MA and/or high between-study heterogeneity. High levels of heterogeneity across primary studies result in MAs that are unreliable and that risk producing biased pooled results because of the excessive influence of just one or two larger studies.
There are many aspects of both SRs and MAs that, despite the use of widely recommended tools, such as the OHAT Risk of Bias scale [27] and the GRADE scheme for assessing strength of evidence [28], involve inherently subjective decisions. Such subjectivity can lead to significant variation across the reviews, even when the same primary studies are being assessed. The potential for subjectivity requires clear-cut independence of the reviews’ coauthors from all influences that might lead to bias—conditions that were clearly not met in the WHO-commissioned SRs.
In summary, the ICBE-EMF evaluation of the SRs exposes major problems with at least 10 or 11 of them. In addition to the scientific quality of the less-than-balanced reviews, they appear to be biased with a strong conviction of nothing but heat to worry about with RF and microwave radiation, in apparent support of the ICNIRP guidelines [26].
The ICBE-EMF article showed that the MAs in the SRs suffered from relatively few primary studies available for each MA (some due to excessive subgrouping), exclusion of relevant studies, weaknesses in many of the included primary studies, high between-study heterogeneity, and/or the lack of a basis for analyzing complex processes, such as those involved in cognitive functions.
Simply put, the criticisms and challenges encountered by those WHO SRs, aside from the most recent one, are serious and severe, including calls for retraction. In addition to the scientific quality of the less-than-balanced reviews, the unsubtle message, in attempts to prop up the ICNIRP position that cellular mobile phone RF radiation and radiation from other wireless communication devices does not pose a health risk, can hardly be mistaken. The systematic reviews displayed unequivocal but misguided bias for the ICNIRP RF exposure guidelines for human safety, with faulty scientific analysis and justification.
In the words according to Microwave News [29], “WHO gets a ‘Failing’ grade on RF systematic reviews: faulted for bad analysis and ICNIRP bias.”
A huge opportunity exists to rethink the everyday electromagnetic environments and technologies most people are exposed to and create more bio-friendly versions of them. Doing so can help reduce risk, drive innovation, and grow the wellness economy. This is especially true for wellness real estate, the fastest-growing sector of the global wellness industry.
With regard to EMF exposure standards and guidelines, even relatively low intensity exposures below permitted exposure levels can have biological effects. While the greatest degree of publicity related to exposures is given to cancer risk and EHS being associated with environmental exposures, numerous other health conditions are indicated as being negatively affected and create high levels of financial burden. Such evidence provides strong reason to create healthier electromagnetic environments and technologies.
Another reason for addressing such issues is that many regulations and guidelines related to EMF exposures are getting stricter, so proactively addressing this trend can help future-proof industries. This type of approach can further open-up opportunities for innovation for those observing market trends and who seek to create “multiple layers of benefit” solutions.
The insurance industry’s perspective on EMF risks provides further evidence of why developing solutions is of paramount importance. The need to effectively address this issue is further highlighted from the documentation of the wide range of health effects associated with EMF exposures, and the costs that these can create to national economies.
Those findings provide strong evidence for the need to apply the precautionary principle with regard to electromagnetic pollution and the need to see how such issues can be better addressed. In particular, it is suggested that proactive precautionary approaches can be adopted by members of the wireless and tech industries enabling them to reframe themselves as future-compliant and future-oriented, which will increase their attractiveness to investors and help them make greater inroads into the global wellness economy through creating more bioelectromagnetically friendly technologies. The health industry also stands to be able to expand its mission through helping develop more bioelectromagnetically friendly environments.
Such approaches will allow EHS accessibility requirements, which a growing body of authorities are taking ever more seriously, to be more easily addressed while creating extra value and reducing risk to other members of society who may also be negatively affected by electromagnetic pollution.
Calls for more bio-friendly environmental exposures are likely to increase as consumer education on these issues increases. The trend for building certification initiatives that reward proactive measures that positively impact health and wellbeing is in line with this and can already be coupled with existing initiatives to improve environmental conditions and incorporate new innovations as they arise through multidisciplinary interventions.
Fortuitously, not all exposures to electromagnetic phenomena are harmful, and some types of artificially created EMF exposures (when used correctly) benefit both health and productivity. There are, in addition, technological breakthroughs that allow increased technical efficiency while reducing exposures to electromagnetic pollution. This is particularly heartening and suggests that in addition to the low EMF tactic often advocated to address electromagnetic pollution issues a more proactive approach can be taken to help biologically optimize the bioelectromagnetic characteristics of environments, sometimes beyond what nature itself can even achieve. Bioelectromagnetic design can drive innovation, reduce risk, and take the design and operation of technologies and environments to a whole new level, creating potential “Win/Win” solutions for all stakeholders that are kind to people, planet, and profit.
Objective: Our knowledge on the prevalence of self-reported sensitivities to environmental factors is poor. The lack of accepted criteria/assessment makes findings of different studies difficult to compare; the way of assessment might play a role in the reported prevalence rates. The present study aimed to report the prevalence rates of five environmental sensitivities for the German general population, to compare three of them with Swedish and Finnish data, and to demonstrate the impact of strictness of criterion on the results.
Methods: Data from a German (n = 2515), a Swedish (n = 3253) and a Finnish (n = 1467) population-based survey was used. Sensitivities were rated on ordinal scales in all samples.
Results: In the German sample, about 25 % of participants reported mild reactions to sounds, chemicals, and buildings, and about 10 % to electromagnetic fields (EMFs) and wind turbines, with a similar pattern for strong reactions, but with proportions of 1-2 %. Data from the Nordic countries show consistent similarities between these two countries, with prevalences exceeding 34 % for mild reactions to chemicals and sounds and about 5 % to EMFs, with a similar pattern for strong reactions, but with proportions of 1-8 %. Prevalence of sensitivity to EMFs was higher, whereas prevalence of sensitivity to chemicals and sounds was lower in Germany. Classification criteria significantly impacted the reported prevalence rates.
Conclusion: Various environmental sensitivities affect a considerable proportion of the general populations of the three countries. To improve comparability, self-report assessment of sensitivities should be based on at least an ordinal scale instead of the widely used yes-or-no question.
Excerpt
The current study has both strengths and limitations. It represents the most comprehensive epidemiological assessment of environmental sensitivities in Europe, including samples being population-based and of large sizes that enhance representativeness to the general populations in these countries. Another strength is the study of five major types of environmental sensitivity, providing broad understanding, and enabling direct comparison between them. Yet another strength is the use of two, rather than typically one, level of strictness of criterion for assessment of prevalence of sensitivities. However, an obvious limitation is the different questions and response alternatives used for the German vs Swedish/Finnish samples; most importantly, symptoms are explicitly mentioned in the German survey, whereas the Swedish/Finnish questions referred to sensitivity. This calls for caution when comparing results from the German and Nordic countries. Another limitation is the relatively low response rate that may result in selection bias, and thus impacting on representativeness. Furthermore, the sampling method used for the Swedish and Finnish samples was the same, but different from that of the German sample, making comparison between these countries more difficult. Also, the different time points for assessment in the included countries might also limit the comparability. Finally, sensitivity was assessed via self-reports thus does not necessarily reflect confirmed environmental health effects.
Amit Verma A, Kumar V, Singh AR. SAR and Temperature Rise in Human Tissues Under 5G Electromagnetic Wave Exposure: A Numerical Study. Indian Journal of Pure & Applied Physics. 64(3). 2026. doi: 10.56042/ijpap.v64i3.22289.
Abstract
The rollout of fifth-generation (5G) wireless networks is driving the pervasive exposure to high-frequency electromagnetic fields, in the range (28–60 GHz), to a new scale. These are faster in carrying out data, but possible thermogenic effects on human tissue have raised concerns. This study aims to investigate the numerical modelling of channel-specific absorption rate and associated temperature increase in the human organs for 5G exposure based on Maxwell’s equations. Simulations were performed at different frequencies (28, 38, and 60 GHz) and exposure durations (6 and 20 min) in the visual part (skin and subcutaneous fat) and in/on the structures of the human head (eyes, brain, skull, ear canal, thyroid, wrist, chest). Results suggest that the SAR increases with frequency and has a maximum value in superficial tissues, whereas the temperature rise is strongly associated with both SAR and exposure time. The most sensitive tissues are the cornea, ear canal, which show temperature increases larger than 3 °C at 60 GHz for long exposure, even if SAR values stay under internationally accepted safety levels. The results indicate that 5G EMW Waves at frequencies are of negligible risk to deep tissues despite a small elevation in temperature due to resonant absorption within the skin, with localized heating of the skin surface becoming of concern given ultra-close proximity exposure of long duration to devices operating at or near 5 G frequencies. The research highlights the need to incorporate thermal safety evaluations into existing exposure standards and proposes more looking into the long-term biological impacts of prolonged exposure to 5G.
Open access: https://or.niscpr.res.
The human body emits a bioelectromagnetic field primarily generated by the electrical activity of the heart, with additional contributions from the brain, muscles, and peripheral nerves. These endogenous fields are not isolated and can be modulated by external electromagnetic and magnetic influences. Current evidence suggests that the main mechanisms underlying such interactions include modulation of ion channels, radical pair dynamics, and ion cyclotron resonance. Several studies report sex-specific differences in responses to magnetic exposure. The main factors implicated in these differences include heart orientation and position, heart mass, tissue conductivity, hormonal modulation, autonomic balance, and cortical field organization. Beyond sex, consistent findings demonstrate that biological effects depend not only on field intensity and frequency but also on polarity (north/south), and direction (vector angle). These parameters are often overlooked or unreported in published works. Some observations even suggest a direct relationship between polarity and sex, with divergent physiological and behavioral outcomes. Recognizing these interactions is crucial to refining models of magnetoreception, resolving inconsistencies, and advancing therapeutic applications of electromagnetic fields. This review integrates evidence from magnetobiology and sex-based physiology to propose that hormonal and structural dimorphism may modulate biological responses to magnetic field. Potential mechanisms involving ion-channel modulation, magnetite orientation, and radical-pair dynamics are outlined and experimental paradigms to test these interactions are proposed. Together, these insights establish a framework for studying sex-dependent magnetic sensitivity in living systems.
Plain language summary
Our bodies naturally produce a bioelectromagnetic field. The heart is the strongest source, but other organs and tissues also contribute. These fields can be influenced by external magnetic or electromagnetic forces, such as those produced by magnets or induction coils. The way living systems respond to these fields depends on many factors. Those are not just signal amplitude and frequency, but also polarity (north/south), and direction (vector angle). There is also evidence that responses may vary according to sex. In fact, multiple studies show that magnetic and electromagnetic exposure can affect sleep, stress responses, and hormone levels differently in males and females. Similar effects have been observed in animals, plants, and even cell cultures. It is supposed that differences in heart size and position, body composition, hormone levels, and nervous system activity can all influence the way the body generates and interacts with electromagnetic fields. Some findings even suggest that magnetic polarity may interact with biological sex in a dependent manner, for instance, one polarity may stimulate men while inhibiting women, and vice versa. These insights help explain why studies on magnetic exposure sometimes report inconsistent results. Ignoring sex differences or magnetic field characterizing variables can lead to confusion and slow progress in this field. By considering these factors, researchers may improve our understanding how magnetic fields interact with living organisms. Notably, this knowledge could open the door to new and more effective medical treatments using magnetic and electromagnetic fields.
The present study investigates the impact of RF-EMF (900 and 1800 MHz) emissions from mobile phone base stations (MPBS) as well as from mobile phone usage on the hematological parameters and stress markers of exposed individuals. Members of MPBS highly exposed (N = 50) and a reference group (N = 51) were tested using a complete blood count and two stress markers, amylase and cortisol. Different effects were found for different blood parameters, based on various combinations of exposure type, demographics, and lifestyle behaviors. Subsequent stepwise regression analysis revealed that exposure from MPBS contributed significantly to TLC, while various combinations of gender, age and power density contributed significantly to differential and absolute basophil counts and absolute monocyte counts. MPBS exposures contributed to absolute monocytes similar to smoking. Furthermore, hours of daily mobile phone exposure together with age contributed significantly to absolute and differential basophil counts and absolute lymphocyte counts. Of concern, almost a quarter of those with high MPBS exposures had basophil counts above the clinical reference limits, while over half of those with heavy daily mobile phone use (4 to 6 hours) had lymphocyte counts above the limits, and most were under 30 years old. While smoking and age contributed to amylase levels, no exposure variables contributed to amylase or cortisol levels. Altogether, there is an indication that RF-EMF from mobile phones and MPBS together with age and gender can differentially impact leucocytes, indicating biological stress and potentially affecting health. These results suggest the necessity for increasing awareness regarding adverse effects of RF-EMF exposures.
Plain language summaryThis study aimed to test whether people who live closer to mobile phone towers (MPBS) and those with greater mobile phones' use show any changes in their red and white blood cells, or to their stress hormones. Two groups of volunteers were recruited, a reference group of those living more than 300 m away, and a highly exposed group, living less than 60 m away from the closest MPBS. Blood samples were taken from both groups and analyzed. The strength of the radiofrequency signal from the MPBS in participants’ homes was measured, and mobile phone use, lifestyle factors, and demographics that could affect the blood parameters were also recorded. Results showed that different white blood cells were affected by different combinations of gender, age, smoking, many hours of daily mobile phone use and high exposures from MPBS. Concerning effects on lymphocytes were found in a large group of residents under 30 years old with high daily mobile phone use (4 to 6 hours). These results indicate human biological systems are under stress from both mobile phone use and local mobile phone tower exposures, leading to potential health effects. Placement and signal strength from MPBS, and guidance regarding daily mobile phone use need to be informed by these results.
Excerpts
The study was conducted in 2022 and 2023 in Aizawl city (23.8789° N and 92.8976° E). Ten mobile phone base stations erected in densely populated areas of the city and operating in two frequency ranges of 900 MHz and 1800 MHz were measured....
Around each mobile base station, a minimum of two people were sampled. Participants were recruited via door knocking of all houses around the towers, mostly in the evenings during both weekdays and weekends....
The highly exposed group comprised 50 individuals over 18 years in good health and living within a 60-meter radius of a MPBS. Similarly, the reference group consisted of 51 individuals in good health who resided at least 300 meters away from any MPBS, matched to the highly exposed group in terms of gender and age. Participants were selected so as to ensure that the majority of their exposure came consistently from the local MPBS and not from work exposures, in the following ways. Participants who were included in the highly exposed group as well as about half of the reference group were those who stayed at home during the day due to being home-makers or unemployed. Furthermore, participants who were included in the reference group (i.e. living more than 300 m from the MPBS) were screened to ensure that they were not being highly exposed at work (i.e., that any MPBS near to their workplace was also more than 300 m away). Selection also ensured that there were no electric transformers, high voltage electrical power lines, radio transmitters, or television transmitters within 500 m of any of the participant’s homes, so as to minimize any effects from these potentially confounding factors. summarizes the characteristics of the ten MPBS....
Measurements for radio-frequency power density emitted by the base
stations were taken in 50 houses, in the living room of each
participant. A HF-60105V4 spectrum analyzer (Germany) was used for all
RF measurements. Measurements were taken by a trained physicist
competent in the use of the spectrum analyzer, who determined the
average power density for the frequencies that were present (which was
necessary because there is no official Indian government register for
the region that describes tower placement and frequencies). Frequencies
of 900 MHz and 1800 MHz were determined to be present in most
residences, due to several towers being close by. The maximum recorded
power density was 7.22 mW/m2 (1.65 V/m) near base station number 5 (see ). The safety limits for public exposure from mobile phone base stations are set to 0.45 W/m2 (450 mW/m2; 13 V/m) for 900 MHz and 0.90 W/m2 (900 mW/m2;
18.4 V/m) for 1800 MHz frequency as prescribed by the Department of
Telecommunications, Ministry of Communications, Government of India, New
Delhi guidelines (DoT Citation2013). The distance from each residence to the nearby MPBS was determined using a digital laser tape measure (Bosch, GLM)....
Background: The rapid increase in the number of Mobile Phone Base Stations (MPBS) has raised global concerns about the potential adverse health effects of exposure to Radiofrequency Electromagnetic Fields (RF-EMF). The application of machine learning techniques can enable healthcare professionals and policymakers to proactively address concerns surrounding RF-EMF exposure near MPBS.
Objective: The current study aimed to investigate the potential of machine learning models for the prediction of health symptoms associated with RF-EMF exposure in individuals residing near MPBS.
Material and methods: This analytical study utilized Support Vector Machine (SVM) and Random Forest (RF) algorithms, incorporating 11 predictors related to participants' living conditions. A total of 699 adults participated in the study, and model performance was assessed using sensitivity, specificity, accuracy, and the Area Under Curve (AUC).
Results: The SVM-based model demonstrated strong performance, with accuracies of 85.3%, 82%, 84%, 82.4%, and 65.1% for headache, sleep disturbance, dizziness, vertigo, and fatigue, respectively. The corresponding AUC values were 0.99, 0.98, 0.920, 0.89, and 0.81. Compared to the RF model and a previously developed model, the SVM-based model exhibited higher sensitivity, particularly for fatigue, with sensitivities of 70.0%, 83.4%, 85.3%, 73.0%, and 69.0% for these five health symptoms. Particularly for predicting fatigue, sensitivity and AUC were significantly improved (70% vs. 8% and 11.1% for SVM, Multilayer Perceptron Neural Network (MLPNN), and RF, respectively, and 0.81 vs. 0.62 and 0.64, for SVM, MLPNN, and RF, respectively).
Conclusion: Machine learning methods, specifically SVM, hold promise in effectively managing health symptoms in individuals residing near or planning to settle in the vicinity of MPBS.
The Possibility of Concentrating Microwave Radiation at Certain Points of the Endothelium of Blood Vessels
Material and Methods: Previously, when studying the effects of electromagnetic fields and radiation on the human body, only thermal processes were taken into account. In this case, the calculated SAR method and the experimental method of tissue equivalent phantom dummies were used, as a rule. Also, their implementation assumed, as a rule, that the absorbing medium is single-phase. This did not take into account the effects asso- ciated with the fact that biological tissue is a mixture of components whose dielectric permittivity differs tenfold, and the particle sizes of the phase components, as a rule, do not exceed one millimeter. The article presents the results of using a computer model that makes it possible to analyze the uneven distribution of the electric field in blood vessels. Computational experiments were performed using the author’s computer program based on the finite element method.
The structure of the tissue containing blood capillaries was imitated by matrix systems containing cylindrical inclusions, the sections of which were characterized by round and rectangular shapes. Computer experiments have been carried out to calculate patterns of spatial distributions of electric field strength. The values of the dielectric constant of the matrix and inclusions, the relative sizes and relative positions of the inclusions varied. The processes were considered stationary and axisymmetric.
Results: It was found that blood vessels can focus the external electric field of microwave radiation on some points of their internal surfaces. The de- gree of concentration is characterized by the parameter k = E/E0, which is equal to the ratio of local tension to the average for the tissue. A significant anisotropy of the concentration effect was found. If the microwave radiation is directed perpendicular to the axis of the cylindrical vessel, the field strengths inside the capillary and in the surrounding tissue are close to each other, there is no concentration effect. If the external field is directed perpendicular to the capillary axis, there is a significant (tens of times) concentration of tension in the connective tissue surrounding the vessel. It was found that the most significant concentration (k>40) occurs in the areas of vascular branching.
Conclusion: 1). The obtained results can be used in the analysis of the results of the pathological effects of electromagnetic waves on the human body. 2). Attention is drawn to the fact that the endothelium, which performs a number of important physiological functions, falls into the area of concentration of electric field strength. It is suggested that the effect of an electric field on the endothelium can create both carcinogenic and physio- logical effects due to physico-chemical processes initiated by an electric field characterized by high intensity values. 3) It must be borne in mind that the electrical component of the electromagnetic wave fluctuates in time and direction. Therefore, the action under discussion is carried out locally,
This study aimed to investigate the effects of high-frequency (6 GHz) radiofrequency electromagnetic radiation (RF-EMR) exposure on oxidative stress markers and kidney morphology. Our study was designed with 3 groups, each containing 10 animals. These groups were: control, sham, and RF-EMR exposed group. No treatment was applied to the control group; the sham group was housed in the same room under the same conditions and for equal periods of time, except that the generator was turned off. The RF-EMR exposed group was exposed to 6 GHz RF-EMR emitted from the signal generator for 4 hours per day for 6 weeks. At the end of the experimental period, intracardiac blood was collected from animals and plasma oxidant (MDA), antioxidant (SOD, CAT and GSH) and cortisol markers were analyzed. After, the rats in all groups were sacrificed and kidney tissues were removed. Hematoxylin and eosin staining methods were applied histopathologically. Blood-plasma GSH, CAT, SOD and MDA levels (excluding cortisol) were lower in the RF-EMR exposed group compared to the control and sham groups (p < .001). No significant difference was observed in plasma levels GSH, CAT, SOD, MDA and cortisol activities between control and sham groups. In addition, we reported that the histological characteristics of kidney tissue were affected by RF-EMR. The results of our study indicated that 6 GHz RF-EMR can function as an environmental stress factor and can modulate oxidative stress in blood plasma and cause morphological changes in kidney tissue.
HighlightsTomar AK, Jha N, Priyadarshini E, Gautam R, Nirala JP, Rajamani P. Effects of industrial, scientific, and medical (ISM) band frequency 2.45 GHz on membrane integrity and oxidative stress of human skin bacteria. Int J Radiat Biol. 2026 Feb 26:1-15. doi: 10.1080/09553002.2026.2636305.
Abstract
Purpose: To investigate the effects of 2.45 GHz radiofrequency radiation (RFR) on oxidative stress and membrane integrity of human skin bacteria.
Materials and methods: Cultures of Staphylococcus epidermidis, Micrococcus luteus, and Enterobacter cloacae were exposed to 2.45 GHz RFR. Oxidative stress was assessed by quantifying hydroxyl (•OH) and superoxide (O2•-) radicals and total intracellular ROS (DCFH2-DA assay). Lipid peroxidation (MDA levels) and protein carbonyl content were measured as oxidative damage markers. Membrane integrity was examined by SEM and TEM imaging and by evaluating protein and carbohydrate leakage. All experiments were performed with at least three independent biological replicates.
Results: RFR-exposed bacteria exhibited a marked increase in ROS generation compared to sham and control groups. Total intracellular ROS, hydroxyl radicals, and superoxide radicals were significantly elevated (∼ 2 fold), indicating strong oxidative stress induction. This biochemical stress correlated with structural alterations: SEM and TEM revealed disrupted cell membranes and cytoplasmic disorganization. Functionally, exposed bacteria showed enhanced membrane permeability, evidenced by substantial leakage of proteins and carbohydrates into the extracellular environment. Furthermore, oxidative damage was confirmed biochemically, with significantly elevated malondialdehyde (MDA >1.5 fold) levels reflecting lipid peroxidation, and increased protein carbonyl (>2 fold) content indicating oxidative modification of proteins. These effects were consistent across all three bacterial species, although E. cloacae demonstrated more pronounced damages. Collectively, these findings highlight a clear link between RFR-induced ROS overproduction, oxidative macromolecular damage, and compromised cellular integrity.
Conclusions: Exposure to 2.45 GHz RFR induces oxidative stress, membrane disruption, and macromolecular leakage in skin-associated bacteria, suggesting possible risks to skin microbiome stability under high-RFR environments.
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Correction: Loughran et al. Radiofrequency Electromagnetic Field Exposure and the Resting EEG: Exploring the Thermal Mechanism Hypothesis
Loughran SP, Verrender A, Dalecki A, Burdon CA, Tagami K, Park J, Taylor NAS, Croft RJ. Correction: Loughran et al. Radiofrequency Electromagnetic Field Exposure and the Resting EEG: Exploring the Thermal Mechanism Hypothesis. Int. J. Environ. Res. Public Health 2019, 16, 1505. International Journal of Environmental Research and Public Health. 2026; 23(2):157. https://doi.org/10.3390/
No abstract
Open access: https://www.mdpi.com/1660-
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Highlights
• Exposure to high voltage power lines was associated to dementia mortality.
• If causal, 1.01% of Alzheimer’s disease cases could be attributed to HVPL exposure.
• Associations for railway ELF-MF with dementia mortality were less consistent.
• Other neurodegenerative diseases were not related to ELF-MF exposure.
We report a non-thermal mechanism by which sub-terahertz (sub-THz) radiation accelerates DNA base pairing in aqueous environments. By using a randomized 40-mer DNA pool as a model system, we investigated the effects of 0.1 THz continuous-wave irradiation on rehydration-coupled structural reorganization. UV absorption spectroscopy revealed a selective enhancement of the G:C base pairing-associated spectral component under this irradiation, in contrast to conductive heating, which suppressed this component. Fluorescence correlation spectroscopy using a base-pair-sensitive dye further demonstrated that 0.1 THz irradiation increased the population of base-paired DNA molecules, while heating induced the opposite effect. These findings indicate that sub-THz waves promote nucleobase-specific hydrogen bonding, potentially by altering non-specific base-stacking interactions, in a manner inconsistent with thermal activation. This study provides mechanistic insight into the physical basis of sub-THz radiation-mediated modulation of nucleic acid structure and dynamics, with implications for the noninvasive manipulation of biomolecular processes.
Conclusions
This work demonstrates that sub-THz irradiation can non-thermally accelerate specific DNA bp formation in aqueous solution under non-equilibrium hydration conditions. Our findings suggest a promising strategy for the gentle modulation of DNA base-pairing-mediated molecular processes under physiological conditions.
Abstract
Excerpt
One of the most important patterns is the disproportionate sensitivity of early developmental stages across taxa. Heatmap analysis of laboratory data (Fig. 4) revealed that embryos and larvae of fish, crustaceans, polychaetes, and echinoderms exhibited consistently higher rates of EMF related effects compared with juveniles and adults. For example, 93% of early-stage fish studies reported significant impacts, compared with 73% of juveniles and 53% of adults. Crustaceans showed a similar pattern, with 100% sensitivity in early stages but only 41% in adults. By contrast, molluscs and other invertebrates showed comparatively low responsiveness, particularly at adult stages.
Abstract
- Reducing the electric field generated by overhead transmission lines is challenging, given that prolonged exposure can affect both humans and the environment.
- The implementation of SCA to minimize the electric field produced by overhead transmission lines stands out for its optimization efficiency and its ability to generate stable and consistent solutions.
- The precautionary principle is particularly relevant when dealing with electric fields generated by overhead transmission lines. Requires acting prudently: conducting studies, establishing controls, and adopting measures to mitigate potential risks.
In summary, while temporal correlations are consistent across multiple outcomes and geographic regions, the absence of large, prospective, individual-level studies with rigorous confounding control means that most reported associations currently reflect correlation rather than proven causation. Future research must prioritise standardised, satellite-derived exposure metrics and multi-centre prospective designs to advance the evidence base beyond Level 3–4.
Future directions and conclusions
This review consolidates evidence that solar activity and geomagnetic disturbances influence human health across cardiovascular, autonomic, circadian, neurological, psychological, and immunological domains. The most reproducible associations involve acute cardiovascular events and autonomic dysregulation during major geomagnetic storms, whereas neurological, psychological, and infectious-disease links remain preliminary. By integrating heliobiology, solar-terrestrial physics, and clinical research, the work establishes space weather as an under-recognised environmental determinant of health with direct relevance for public health policy, clinical practice, and human spaceflight.
[Determination of exposure to electromagnetic fields from electric mobility]
After a comprehensive literature review and the optimization and development of suitable measurement methods, systematic measurements were carried out at a selection of charging points and purely electrically powered passenger vehicles (BEV). The selection of vehicles and charging points was made in such a way that the current technologies and charging processes are recorded as representatively as possible. Regarding conductive (cable-based) charging, all common charging modes were tested, i.e. AC charging at 230 V (mode 2), AC charging at 400 V (mode 3 at 11 kW wallbox and 22 kW charging station), as well as DC charging at two different fast-charging stations (mode 4 at 300 kW and 350 kW stations). When selecting the vehicle, care was taken to ensure that the range of possible charging capacities of modern BEV was as wide as possible. Due to its lack of widespread use, inductive (wireless) charging could only be examined at a pilot installation for charging taxi vehicles.
Measurements during conductive charging were carried out for different vehicle-to-charging- point combinations and different battery charge states (< 10 % and > 95 %) were considered for both conductive and inductive charging. For situations in which the measurement results led to exposure values above the reference values recommended by ICNIRP in 1998 and 2010, additional numerical calculations with anatomical body models were carried out and the results were compared with the respective basic restrictions.
The measurement and calculation results showed that for the investigated charging technologies in typical exposure scenarios corresponding to common behavior, no exceedances of basic restrictions for the general public according to the ICNIRP 1998 and 2010 recommendations are to be expected. This finding is also consistent with the literature available to date.
However, local exceedances of reference values for the general public are possible with both, conductive and inductive charging in normally accessible areas. In the case of conductive charging, these local exceedances of reference values were caused by transient processes with comparatively high peak values of magnetic flux density in the initiation phase of the charging process. During the stationary conductive charging process, no exceedances of the reference values were detected in the usual occupied area. The utilization of the reference values is typically in the lower single-digit percentage range and below. Particularly with DC charging, the utilization of the reference values typically remains well below 1 %. Only directly at the charging cable or at the charging plug, magnetic flux densities during AC charging were observed that were slightly above the reference values, even during stationary charging, but not during DC charging.
Based on the current ICNIRP evaluation paradigm, DC charging turned out to be less relevant in terms of radiation protection (lower exposure indices) than AC charging.
In the case of the inductive charging system investigated, the maximum magnetic field immissions inside and in the immediate vicinity outside the vehicle are determined by the stationary charging process, no relevant transients when switching the 85 kHz energy transmission on and off could be observed. Only at the driver's seat of the examined vehicle transients in the initial phase were observed, which, evaluated according to the ICNIRP recommendations, led to somewhat larger exposure indices in the foot area than the immissions during stationary charging. In the typically occupied area inside the examined vehicle, the measured magnetic field immissions locally reached the mid-double-digit percentage range of the reference level for the general public according to ICNIRP 1998.
Outside the vehicle, along the vehicle perimeter at street level, local exceedances of 5 to 6 times the reference level for the general public according to ICNIRP 1998 occurred but quickly decreased with increasing height above street level, thus no exceedances from approx. 50 cm above street level could be observed.
When comparing conductive and inductive charging systems from a radiation protection point of view, the measurements and calculations carried out indicate that conductive AC charging is more relevant from a radiation protection point of view with regard to short-term exposure peaks and inductive charging with regard to long-term average exposure.
With regard to the exposure of persons with electronic implants, the measurements carried out for the charging systems examined also do not provide any indications of electromagnetic interference with the implants.
Scarato T. U.S. policy on wireless technologies and public health protection: regulatory gaps and proposed reforms. Front. Public Health, 18 December 2025. Volume 13. doi: 10.3389/fpubh.2025.1677583.
Abstract
The current U.S. regulatory framework governing non-ionizing radiofrequency radiation (RFR) used in all wireless technology is outdated and lacks adequate protection, oversight, and enforcement. The U.S. Federal Communications Commission (FCC) was given regulatory jurisdiction by the U.S. Congress in 1996 over RFR exposure standards setting even though FCC has no in-house expertise regarding health or environmental effects from RFR. FCC is a licensing/engineering entity that relies on other government agencies for guidance on ambient exposures and devices. However, all relevant civilian public health and environmental agencies have been defunded from non-ionizing radiation research activities and oversight. Thus, current regulations have remained unchanged since 1996. Human exposure limits are designed to protect against short-term high-intensity effects, not today's long-term chronic low-intensity exposures. Scientific evidence indicates that children's thinner skulls, unique physiology, and more conductive tissues result in significantly higher RFR absorption rates deeper into critical brain regions, which are still in development and thus more sensitive to environmental insults. However, current policies offer no safeguards for children/pregnancy or vulnerable populations. Growing research also indicates risks to wildlife, especially pollinators. In 2021, a U.S. federal court mandated that the FCC show proper review of growing scientific evidence, after a cursory FCC re-approval of limits in 2019, but FCC has yet to respond. This paper explores regulatory infrastructure deficiencies, including the absence of monitoring/oversight, premarket safety testing, post-market surveillance, emissions compliance/enforcement, occupational safety, and wildlife protection. Compliance tests for cell phones do not reflect real-world consumer use and can therefore camouflage exposures that exceed even FCC's outdated limits. Other countries enforce stricter limits, robust monitoring, transparency measures, and compliance programs with additional policies to protect children. Also discussed is the chronic revolving door between FCC leadership and the wireless industry, resulting in a state of regulatory capture. Policy recommendations for common-sense reforms are made for reinvigorating independent research, developing science-based safety limits, ensuring pre- and post-market surveillance, and improving oversight/enforcement, as well as implementing risk mitigation to reduce exposures to children, vulnerable groups, and wildlife.
Discussion and conclusion
What has emerged from this review is a profound failure of governance, with the U.S. as an exemplar of regulatory gaps. While wireless technologies are rapidly advancing to 5G and beyond, U.S. regulatory oversight has failed to keep pace. The current regulatory framework governing wireless technology in the U.S. is outdated, fragmented, and heavily influenced by industry. Assumptions that federal safety limits are current and science-based are inaccurate, as today's guidelines are based on decades-old research, obsolete/incomplete test methods, and a landscape marked by a near-total absence of civilian research, oversight, and enforcement activity (10). Given the ubiquity of wireless in modern workplaces, the lack of a comprehensive occupational RFR/EMF program, exposure research, and medical surveillance represents a serious gap. This issue should command newfound attention.
The existing research paralysis has led to significant regulatory deflection and abdication. Local and state officials defer to federal agencies. Federal agencies defer to one another. Yet, there has not been an evaluation of all the scientific evidence regarding the health effects of wireless technologies despite major technological changes and an ever-growing body of science. Agencies that policymakers expect to have studied the issue simply have not done so.
The result is that U.S. regulations exist without an up-to-date review. Exposure limits are based only on protecting short-term exposures, ignoring the realities of today's long-term cumulative exposure and complex modulations and signaling characteristics reported as important variables. Nothing has changed since 2002, when the EPA wrote that “…federal health and safety agencies have not yet developed policies concerning possible risk from long-term, non-thermal exposures” (321).
To rectify the current situation, government oversight must balance industry power. A strong regulatory framework must be built that rests on transparency and robust evidence-based evaluation, free of industry influence. Prevention is the cornerstone of public health, and the U.S. needs to move toward a risk mitigation approach.
Advancing regulatory reforms is not just a matter of good governance but an ethical imperative. The consequences of ignoring the growing science on non-thermal impacts could be severe, not only for irreversible health impacts, but also for economic impacts, worker productivity, educational outcomes, and environmental damage. The U.S. should take a leadership role in technology safety by putting children, vulnerable groups, and environmental protection at the center of our decision-making process.
Open access: https://www.frontiersin.org/