Monday, September 8, 2025

Recent Research on Wireless Radiation and Electromagnetic Fields

I have been circulating abstracts of newly-published scientific papers on radio frequency and other non-ionizing electromagnetic fields (EMF) monthly since 2016. The complete collection contains more than 2500 abstracts with links to these papers. Several hundred EMF scientists around the world receive these updates.

To download Volume 3 which contains abstracts of papers published since 2024 
(including the new papers listed below) click on the following link (468 page pdf):

To download Volume 2 which contains abstracts of papers published from 2021 through 2023 
click on the following link (867 page pdf):

To download Volume 1 which contains abstracts of papers published from 2016 through 2020 
click on the following link (875 page pdf):

The abstracts for recently published papers appear below.

 



A Systematic Review of the Impact of Electromagnetic Waves on Living Beings

Danho S, Escobar Huertas J, Schoellhorn WI (August 17, 2025). A Systematic Review of the Impact of Electromagnetic Waves on Living Beings. Cureus 17(8): e90355. doi:10.7759/cureus.90355.

Abstract

The effects of electromagnetic fields (EMFs) have been extensively debated among researchers and the public, with their critical consequences often dismissed or deemed unscientific. In light of this, we conducted this systematic review that extensively focuses on the detrimental effects of EMFs on living organisms.

A comprehensive and systematic literature search was performed on various electronic databases, including PubMed, Scopus, and the Cochrane Library, using Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. This review concentrates on experimental studies published between 2017 and 2024 that investigated physiological or behavioral responses to EMF exposure, with particular attention given to those reporting harmful or concerning effects. Documented impacts include effects on humans, animals, and plants, targeting various cell types (e.g., blood, cancer, thyroid, cochlea), genotoxicity, cardiovascular parameters (e.g., heart rate, blood pressure), male fertility (e.g., testes, sperm), neuronal brain activity, and photosynthesis in plants. Methodological quality was assessed using established bias assessment tools, and certainty of evidence was evaluated according to the GRADE framework.

After screening, 24 studies were included in the present review; five studies were non-randomized and involved humans, seven studies were in vitro, and 12 studies were conducted on animals. The findings demonstrated that EMFs negatively affect a wide array of biological systems of living organisms, including mechanisms of oxidative stress, inflammatory responses, and disruptions in cellular, physiological, and ecological processes. Most of the included studies showed a moderate to high risk of bias, which contributed to a lower overall certainty of the evidence.

These findings underscore the significant health and environmental risks associated with rising exposure levels of EMF, highlighting the urgent need for strategies to mitigate the risks. Despite these valuable insights, significant research gaps persist because the long-term effects of EMF exposure, especially on human populations, remain poorly understood and warrant further investigation and targeted mitigation strategies.

Conclusions

The rapid evolution of wireless communication technologies continues to introduce new applications and expand into higher frequency ranges. This review identifies many experimental studies reporting the biological effects of EMFs on humans, animals, and plants. These include changes in fertility parameters, cellular responses associated with oxidative stress, developmental outcomes, behavioral alterations, and cognitive effects. Our findings highlight why it is important to take a closer, structured look at how EMF exposure might affect both human health and the environment. This review focused on reported biological effects, without implying universality or disregarding studies that observed neutral or application-related outcomes. The diversity in reported results highlights the need for cautious interpretation and context-specific analysis.

Significant research gaps remain. Short-term effects have drawn much attention in past studies, but the more pressing question (what happens over time?) remains largely unanswered, especially concerning people and species highly sensitive to their environment. Additionally, a lack of standardized exposure protocols and inconsistent reporting of critical parameters such as field strength and frequency limit reproducibility and hampers the formulation of robust exposure guidelines. Addressing these challenges means committing to research that is not rushed, not vague, and not influenced by unclear funding. Long-term, transparent, and solid work is the only way forward. These should include clearly defined exposure parameters, attention to population-specific vulnerability factors (e.g., age, baseline health), and ecological relevance. As seen historically, public concern and scientific controversy can foster critical inquiry and the development of evidence-based safety standards. A coordinated effort is needed to enhance our understanding of EMF interactions with biological systems and to support informed decision-making in public health initiatives and policy.


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Effect of electromagnetic radiations from mobile towers on genetic damage and genetic polymorphism in humans: a review on India’s perspective

Priya, K., Singh, M., Haokip, L. et al. Effect of electromagnetic radiations from mobile towers on genetic damage and genetic polymorphism in humans: a review on India’s perspective. Toxicol. Environ. Health Sci. (2025). https://doi.org/10.1007/s13530-025-00273-9.

Abstract

There have been concerns about possible health implications of radiofrequency electromagnetic radiation owing to increased cell phone use and proliferation of cell phone towers. The amount of RF-EMR energy absorbed in the human tissues relies on both the exposure characteristics of frequency, intensity, and exposure duration. This effect could be due to the exposure of genetic material by RF, resulting in an increased risk of cancer development and death in cells. Genetic polymorphisms involve variation in the DNA sequence in and among people, populations, or groups. These polymorphisms might contribute to susceptibility to RF effects. These genetic variations-which could be in the form of single nucleotide polymorphisms (SNPs) or copy number variations (CNVs-may occur either by a sheer chance process or by external factors such as viruses or radiation. Knowing the influence of genetic polymorphisms on RF exposure would help level off related health risks of cell phone use and cell towers. This scientific review examines related scientific research data about the effects that cell terminal EMR has on human genetic damage and polymorphism. We critically appraise literature and peer review journals relevant to data in assessing our current knowledge in this area. Our study reveals the fact that some studies indicate exposure to EMR does bear a relation with genetic damage, but such results should be further researched as to which health impacts they bring forward.


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Systematic reviews and meta-analyses for the WHO assessment of health effects of exposure to radiofrequency electromagnetic fields, an introduction

My note: Stay tuned ... the ICBE-EMF has a paper to be published soon that provides our analysis of these 12 WHO systematic reviews. 

Verbeek J, Zeeb H, van Deventer E, Ijaz S, Doré J-F, Driessen S, Roth N, Whaley P. Systematic reviews and meta-analyses for the WHO assessment of health effects of exposure to radiofrequency electromagnetic fields, an introduction. Environment International. 2025, doi: 10.1016/j.envint.2025.109751.

No abstract

Introduction

"We, the editors (SI, JFD, SD, NR, PW) and organizers (JV, EvD, HZ) of this special issue of Environment International on the World Health Organization’s (WHO) assessment of the health effects of exposure to radiofrequency (RF) electromagnetic fields (EMF), are pleased to present this collection of systematic reviews of the effects of RF EMF. This issue represents the culmination of four years of meticulous, collaborative work by more than 80 scientific experts from around the world. We extend our sincere congratulations to the authors of the reviews and commend their dedication to producing reviews of such high scientific quality.

This Special Issue includes nine protocols and subsequent twelve systematic reviews, all designed to support the human health risk assessment of RF-EMF exposure. In this editorial, we summarize the processes used to commission and develop the systematic reviews, describe the methodological tools employed, and summarise the key findings. We also reflect on the successes and challenges encountered throughout this ambitious undertaking.

Collectively, these systematic reviews offer a robust model for global health risk assessments, contributing to the development of evidence-based norms, standards, and research priorities. This project stands as one of the most comprehensive evaluations of environmental health evidence to date – an effort from which we continue to learn how to best approach this task (Jarosińska et al., 2018, Pega et al., 2021, Pérez Velasco and Jarosińska, 2022)."

Excerpts

"Although no other mechanisms beyond nerve cell excitation and thermal effect are known to pose health risks (Sheppard et al. 2008), the possibility remains that other, as yet unknown, biophysical mechanisms could exist and potentially lead to health effects."

"The last EHC Monograph on RF fields was published in 1993 (World Health Organization 1993) and is currently being updated to reflect new scientific evidence."

"The approach to developing the overall scientific basis for the updated EHC Monograph on RF Field exposure had three sequential parts: a scoping review, a prioritisation of outcomes, and the set of systematic reviews presented in this special issue."

"For one of the review topics − heat-related effects − a systematic review was not completed. The protocol did not pass peer review process in time and proceeding with it would have significantly delayed the overall project. As a result, this systematic review was decommissioned."

"The systematic reviews report evidence for the effects of RF EMF on all important health outcomes but the number of studies finally included for each outcome varied significantly, ranging from five studies on cognitive function in human observational studies (Benke et al. 2024) to 215 studies on fertility in animal experimental studies (Cordelli et al., 2023, Cordelli et al., 2024).

The systematic reviews of human observational studies on cancer found moderate-certainty evidence of no or only a small effect for several important cancer types, such as glioma and lymphoma (Fig. 1), based on 74 studies/databases (Karipidis et al., 2024, Karipidis et al., 2025). Only for thyroid cancer and oral cavity/pharynx cancer the evidence was respectively low and very low. The review of cancer in experimental animals (Mevissen et al. 2025) identified 10 long-term bioassays and dozens of other studies. Based on only one or two of these studies, the authors concluded that there was high- to moderate-certainty evidence of an effect of RF EMF on five cancer types in animals."

"The review of fertility outcomes in experimental animals yielded the most varied results. It found high-certainty evidence of no or only a small effect on litter size, but also high-certainty evidence of a large adverse effect on male fertility (Cordelli et al., 2023, Cordelli et al., 2024).(Fig. 2) Unfortunately, there were only few human observational studies on fertility that produced only very low-certainty evidence (Johnson et al., 2024, Pw Kenny et al., 2024)."

"For cognition, human experimental studies provided consistent moderate- to high-certainty evidence of no or only a small effect across several domains of cognitive performance (Pophof et al. 2024). (Fig. 3) However, the corresponding human observational review (Benke et al. 2024) included only a few studies with results that were assessed as very low certainty."

"Regarding symptoms, human experimental studies (Bosch-Capblanch et al. 2022) showed moderate-certainty evidence of no or a small effect of RF EMF exposure. Yet again, the limited number of human observational studies resulted in very low certainty evidence (Roosli et al. 2024).(Fig. 4). "

"Finally, the review of effects of RF EMF on oxidative stress (Meyer et al. 2024) found highly variable results, ranging from large increases to large decreases in oxidative markers across all outcomes, even within one homogenous PECO. The certainty of evidence was rated very low largely due to a high risk of bias in the included studies. This was particularly evident in the exposure domain, where many experimental studies still relied on mobile phones to generate exposure – a method prone to bias if not carefully controlled (Kuster and Schönborn 2000)."

"...  separate reviews were conducted for human and animal evidence for fertility and for cancer. This led to clear conclusions of the individual reviews but, as is particularly clear in cases where the animal evidence appears to contradict the human evidence, will necessitate another step of integration of the conclusions of the reviews in an overall conclusion “what this evidence means for human health”. This is the next step still to be conducted by a dedicated WHO Task Group."

"One notable exception was the systematic review on the effects of RF EMF on cancer in experimental animals, which stood out due to its use of a different synthesis method. The authors concluded that there was an effect of RF EMF if two studies showed statistically significant results, disregarding null findings from other studies. This approach deviated from the protocol, which had indicated the use of relative risk as the primary synthesis method (Mevissen et al. 2025). Despite extensive discussions with editors and peer reviewers, the review ultimately concluded that there was high-certainty evidence of an effect on cancer. Whether this method proves valid – and whether alternative synthesis approaches would yield the same conclusion—remains to be seen."

"This complex project has led to high-quality summaries of the evidence of effects of RF EMF on the most important health outcomes reported in the WHO prioritization survey in a standardized and transparent way. The results and conclusions from the present set of systematic reviews provide the most solid achievable basis for further evaluation of the effects of EMF exposure on health by the WHO task group, and the upcoming EHC Monograph of RF fields." 

"Declaration of competing interest

The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: 1. Jos Verbeek received financial support from WHO for preparing this introductory article based on financial support from the Australian Radiation Protection and Nuclear Safety Agency, the Public Health Agency of Canada, the Environmental Protection Agency of Ireland, the Swiss Federal Office of Public Health and the Bill and Melinda Gates Foundation. The funders had no role in the decision to publish or in the preparation of the manuscript. 2. Up until the end of 2022, PW’s contribution to the Special Issue was financially supported by the honorarium he received as an Associate Editor for Environment International. This contract ended in December 2022. From January 2023, PW’s contribution was pro bono as a Guest Editor at the journal. From April 2024 to May 2025, PW provided paid contractual services to WHO on a project to develop systematic review protocols and an evidence-mapping methodology for evaluating health effects of exposure to PFAS chemicals. 3. SI’s time is supported by the National Institute for Health and Care Research Applied Research Collaboration West (NIHR ARC West)."


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Carcinogenicity of Radio-Frequency Radiation: Similarities and Differences Between Outcomes of Two Studies

Peleg M, Berry EM, Deitch M, Nativ O, Richter E. Carcinogenicity of Radio-Frequency Radiation: Similarities and Differences Between Outcomes of Two Studies. Med Discoveries. 2025; 4(7): 1267

Abstract

We discuss the similarities and the differences between two papers published on the carcinogenicity of radio frequency radiation in the military setting with some overlap of the patients’ groups. The first paper reported statistically significant increases of cancer cases while the second did not. We show that the two papers presented similar and non-conflicting characteristics of the reported cancers, mainly high hematolymphoid cancers percentage frequencies and earlier onset of cancers in the exposed group. We think that the conclusion of not identifying carcinogenicity, which is explained in the second paper by not reaching statistical significance, is due to much smaller size of the patients’ group in that paper.

Open access: https://www.meddiscoveries.org/pdf/1267.pdf

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Altered development in rodent brain cells after 900 MHz radiofrequency exposure

Bodin R, Godin L, Mougin C, Lecomte A, Larrigaldie V, Feat-Vetel J, Méresse S, Montécot-Dubourg C, Marcelo P, Mortaud S, Villegier AS. Altered development in rodent brain cells after 900 MHz radiofrequency exposure. Neurotoxicology. 2025 Sep 2;111:103312. doi: 10.1016/j.neuro.2025.103312.

Abstract

Health risks related to 900 MHz 2 G frequency exposure remain inconclusive under current regulatory standards. Research into potential long-term effects is ongoing, particularly as the use of mobile networks and wireless devices increases. This study investigates the effects of non-thermal exposure levels of mobile phone 900 MHz radiofrequency electromagnetic field (RF-EMF) on rodent neurodevelopment. In vivo, the effects of pre- and post-natal 0.08 and 0.4 W/kg specific absorption rate (SAR) exposure were assessed for their impact on the proteomic profile at postnatal day 0 (PND 0). Brain-derived neurotrophic factor (BDNF), BrdU+ proliferative cells, synaptogenesis, and oxidative stress in the hippocampus and cortex of rat pups were studied at PND 8 and PND 17. Effects of the lowest SAR (0.08 W/kg) were assessed in vitro to afford mechanistic data regarding neural stem cells (NSCs) differentiation. In vivo results showed a decrease in BDNF level and BrdU+ proliferative cells with a decrease in synapse balance (excitatory synapses/inhibitory synapses). In vitro, at 0.08 W/kg there was an increase in Ki-67 + proliferative cells, apoptosis, and double-strand DNA breaks in NSCs. A lower ratio of B1 cells (primary progenitors of NSCs) among total cerebral cells and a higher ratio of oligodendrocyte progenitor cells and astrocytes were observed in the exposed NSCs. Our findings suggest that key cellular events for brain ontogenesis are likely to undergo changes with RF-EMF 900 MHz exposure during early development. These support the hypothesis that the developing central nervous system is vulnerable to RF-EMF exposures in rodents at regulatory thresholds.

Highlights

• In vivo exposure reduced cortex cell proliferation, BDNF and synapses balance.
• In vivo exposure reduced hippocampus synapses density and balance.
• Proteomic analysis showed dysregulation of proteins involved in synaptic signaling.
• In vitro exposure increased apoptosis, DNA damage and glial differentiation shift.
• 900 MHz exposure affect rodent neurodevelopmental at regulatory threshold levels.


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Oxidative stress and testicular damage induced by chronic exposure to 35.5 GHz millimeter wave radiation in male Wistar rats 

Gautam R, Jha N, Tomar AK, Nirala JP, Arora T, Rajamani P. Oxidative stress and testicular damage induced by chronic exposure to 35.5 GHz millimeter wave radiation in male Wistar rats. Andrology. 2025 Aug 12. doi: 10.1111/andr.70107.

Abstract

Background: The widespread usage of millimeter waves (MMW) in different spheres of the public domain necessitates to have a better understanding of any possible health impacts caused by them. The latest example of this is the global implementation of 5G technology.

Objectives: The present investigation aimed to study the effects of 35.5 GHz frequency on reproductive parameters of male Wistar rats.

Methods: The study employed a randomized controlled design, with animals being assigned to control, sham-exposed, and exposed groups, with six animals in each group (n = 6). The experimental group was exposed to 35.5 GHz frequency for 2 h per day for 60 days. At the end of the exposure period, various sperm parameters such as sperm count, morphology, viability, and sperm mitochondrial activity were evaluated. The evaluation of oxidative stress was done by lipid peroxidation assay in testis homogenate. Superoxide dismutase, total sulfhydryl level, and total antioxidant capacity were assessed in testis homogenate. The DNA damage in the testis was assessed through the comet assay.

Results: The results showed a significant decrease in sperm viability and count, as well as morphometric changes in testis histopathology. Lipid peroxidation testis was significantly elevated in the exposed group, while superoxide dismutase (SOD), total sulfhydryl level, and total antioxidant capacity were significantly decreased in the exposed group. The comet assay revealed a significant increase in DNA damage in the exposed group, indicating genotoxic effects.

Discussion: The observed changes in sperm parameters, testicular morphology, and oxidative stress markers highlight the potential for testicular tissue damage via oxidative mechanisms. These results underscore the need for further research to elucidate the biological implications of chronic MMW exposure.

Conclusion: Chronic exposure to 35.5 GHz frequency may negatively impact male reproductive function and testicular tissue, primarily through mechanisms involving oxidative stress.


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Prospective long-term follow-up of patients with idiopathic environmental intolerance attributed to electromagnetic fields after a provocation trial

Li KH, Guo HR. Prospective long-term follow-up of patients with idiopathic environmental intolerance attributed to electromagnetic fields after a provocation trial. Ecotoxicol Environ Saf. 2025 Sep 1;303:118944. doi: 10.1016/j.ecoenv.2025.118944.

Abstract

Previous short-term follow-ups of idiopathic environmental intolerance attributed to electromagnetic fields (IEI-EMF) found no patients recovered after receiving provocation trials, and only a small portion were willing to consider something else caused their symptoms, although levels of their symptoms and concerns decreased. Few long-term follow-ups have been conducted, so we conducted a study to fill the data gap. We recruited participants of the initial provocation trial between 2010 and 2015 to assess changes in symptoms and concerns related to EMFs and the reversibility of IEI-EMF. The same questionnaire used in the trial was administered through telephone interviews. Of the 147 participants recruited, 70 completed the follow-up, including 35 IEI-EMF patients and 35 referents. Of the patients, 60 % were willing to consider something else caused their symptoms, and 62.9 % reported recovery from IEI-EMF after the trial in 1.80 years on average, among whom 86.4 % reported idiopathic recovery. Most of the proportions of symptoms and concerns related to EMFs among patients decreased after the trial although changes in concerns between the study groups did not reach significant differences. In conclusion, different from the previous short-term follow-ups, most patients recovered in our long-term follow-up. Most of recovered cases were idiopathic, indicating IEI-EMF is self-limited in most cases given sufficient time. Most of patients were willing to consider something else caused their symptoms, indicating most cases of IEI-EMF might be attributable to nocebo effects. Our findings suggest a possible therapeutic effect of provocation trials, which needs to be confirmed by further randomized controlled intervention studies.

Highlights

Previous studies found no IEI-EMF patients recovered after provocation trials.
We describe the first long-term follow-up of IEI-EMF after a provocation trial.
Most of the patients reported recovery, with 86.4 % being idiopathic recovery.
Most of the patients were willing to consider something else caused their symptoms.

Conclusions

Most participants with IEI-EMF had recovered in the current long-term follow-up study, while none of the participants with IEI-EMF in the two previous short-term follow-ups reported recovery, and most recovered cases in our study were idiopathic. This indicates that IEI-EMF is self-limited in most cases given sufficient time. In addition, provocation trials might accelerate the natural evolution course of IEI-EMF. A relatively large proportion, up to 60.0 %, of participants were willing to consider the possibility that their symptoms might have been caused by something other than EMFs, while the previous short-term studies observed much lower proportions. In addition, the proportion of feeling concerns that EMFs might be threatening their health and feeling worries about EMFs may affect every aspect of their life decreased in the participants with IEI-EMF. However, these did not relieve them from the worries about visualizing large EMF devices in the environment. In conclusion, our findings supported that IEI-EMF may be related to the nocebo effect in most cases. Our study also suggested a possible therapeutic effect of provocation trials when the results are negative, which needs to be confirmed by further randomized controlled trials. These findings might be applied to other types of IEI and cast some light on its etiology.


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Looking for Biomarkers Which May Explain Idiopathic Environmental Intolerance Attributed to EMF (IEI-EMF): Does RF-EMF Exposure Influence Salivary Cortisol Response?

My note: "...  the current study tested predominantly young, healthy adults, the results cannot be generalized to other populations, including children, older adults, or those with poorer health." Since none of the participants were EHS, why do they consider this an IEI-EMF study?

Verrender A, Manley J, Wallace NK, Loughran SP, Croft RJ. Looking for Biomarkers Which May Explain Idiopathic Environmental Intolerance Attributed to Electromagnetic Fields (IEI-EMF): Does RF-EMF Exposure Influence Salivary Cortisol Response? Bioelectromagnetics. 2025 Sep;46(6):e70021. doi: 10.1002/bem.70021. 

Abstract

In order to understand Idiopathic Environmental Intolerance attributed to Electromagnetic Fields (IEI-EMF), it has been argued that it is crucial to test for effects of radiofrequency electromagnetic fields (RF-EMF) on biomarkers, given that they can be more objective than symptom reports. While no clear evidence links RF-EMF exposure to biomarker changes, research remains limited and largely speculative due to the lack of known bioeffect mechanisms. However, there is in vitro evidence that cortisol is affected by heating, which, as RF-EMF causes heating, raises the possibility that RF-EMF exposure may increase cortisol via thermally mediated processes. If cortisol is affected by RF-EMF exposure, it may form part of a broader aetiology of IEI-EMF, where RF-EMF-induced physiological (cortisol) inputs first generate somatic sensations, which are then fostered by expectancy or learning-based processes to generate symptoms. However, studies investigating whether RF-EMF exposure influences cortisol have reported inconsistent, but mostly null results, and many suffer from methodological issues. The current study was designed with several methodological improvements to determine whether RF-EMF affects cortisol. Seventy-two participants completed a randomized, double-blind, counterbalanced provocation study where they were exposed to both active (2 W/kg peak SAR10g in head) and sham RF-EMF (0 W/kg peak SAR10g in head). Despite implementing several methodological improvements, the current study failed to find an effect of RF-EMF exposure on salivary cortisol concentration. This study provides a valuable direction for future research and stresses the importance of establishing and testing theoretically plausible interactions between low-level RF-EMF exposure, the human body, and IEI-EMF symptoms.

Summary

  • The current study incorporated several methodological improvements to test whether exposure to RF-EMF increases salivary cortisol concentration in humans.

  • The current study failed to find an effect of RF-EMF exposure on salivary cortisol concentration, and there was no influence of participants' sex.

  • Given the novelty of the methodological improvements implemented in this study, this lack of effect on salivary cortisol is very robust.


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Navigating Environmental Crossroads: Pesticides, Bee Pollinators, and the Wireless Revolution

Davis D, Malkan S, Ogunseitan OA. (2025). Navigating Environmental Crossroads: Pesticides, Bee Pollinators, and the Wireless Revolution. Environment: Science and Policy for Sustainable Development, 67(5), 3–4. https://doi.org/10.1080/00139157.2025.2518032.

The webinar series hosted by Environment: Science and Policy for Sustainable Develo­pment is open to the public and welcomes ongoing con­versations about strategies for navigating environmental cross­roads. The webinar entitled “Navigating Environm­ental Crossroads: Pesticides, Bee Pollinators, and the Wire­less Revolution” occurred on the Zoom platform on 26 March 2025 with 263 registrants and more than 80 attendees from a broad range of countries. The video recor­ding of the webinar is embedded in the online version of this article, available here: https://doi.org/10.1080/00139157.2025.2518032

Video 1. (1:04:02)

As 2025 unfolds, we find ourselves at a critical environmental crossroads. In early January, wildfires driven by hurricane-force winds swept across Southern California, forcing hundreds of thousands to flee. Nearly 90 square miles burned where urban and wilderness areas meet—another stark signal of a changing climate.Footnote1

The fires were still smoldering on 20 January when the United States announced its withdrawal from the United Nations Paris Agreement.Footnote2 Weeks later, on 12 March, the U.S. Environmental Protection Agency launched what it called the “Biggest Deregulatory Action in U.S. History,” moving to roll back the mercury and air toxics standards, dismantle environmental justice programs, and restructure the agency’s Science Advisory Board.Footnote3

These events framed the launch of a new webinar series by Environment: Science and Policy for Sustainable Development, designed to engage a multidisciplinary audience in seeking solutions to complex challenges at the intersection of science, policy, and sustainability.

Scientific integrity is nonnegotiable. Yet translating research into regulatory policies involves negotiation among stakeholders with competing values. Our best tools for navigating environmental crossroads must maximize transparency and consider trade-offs across One HealthFootnote4—human, animal, plant, and ecosystems—as well as economics, equity, and resource conservation.Footnote5

The first webinar focused on two underrecognized global threats: the impact of neonicotinoid pesticides on bee pollinators and food security, and the growing risks of wireless radiation to all living systems. The session underscored the urgency of turning robust scientific evidence into practical policy—limiting exposures, promoting safer alternatives, and closing critical research gaps.

Neonicotinoids (neonics), the most widely used insecticides in history, have come under intense scrutiny in recent years.Footnote6 While they may protect some crops from pests, mounting evidence suggests they are also contributing to the alarming decline in bee populations worldwide—particularly honey bees, one of over 2,000 species vital to food production.Footnote7 The long-term consequences for pollination and ecosystem stability are profound and deeply concerning.Footnote8

Research on neonics’ broad-spectrum harms has provoked strong resistance from pesticide manufacturers, who often follow the tobacco-industry playbook:Footnote9 casting doubt on science and attacking scientists. These industries fund research programs at universities and push back when government-sponsored studies, such as those from the National Toxicology Program, produce inconvenient results.Footnote10

Simultaneously, our world is increasingly bathed in electromagnetic radiation from mobile phones, Wi-Fi networks, and other wireless technologies. While these tools have reshaped communication and daily life, evidence continues to build around their potential health impacts, especially with long-term exposure.Footnote11 Adverse effects have been observed not only in humans, but also in animals and bee populations.Footnote12,Footnote13

The electronics industry, now the most profitable in history, has shown little appetite for investigating or mitigating these harms. With the rise of generative artificial intelligence and global 5G expansion, exposure will only intensify. Yet industry investment in health risk research remains minimal.

A recent review for the World Health Organization examined 52 experimental studies and found high-certainty evidence linking radiofrequency radiation to tumors of the brain and heart nerves.Footnote14 These findings, led by independent experts, add urgency to calls for applying the precautionary principle.Footnote15

We do not need perfect certainty to take protective action. In many cases, the science is already sufficient to justify precautionary policies. But we must also continue investing in independent research and accelerating the development of safer technologies.

For pesticides, nontoxic alternatives exist—but will not be widely adopted until manufacturers and users recognize the long-term benefits of sustainable practices. The same is true for wireless technology: We can innovate to reduce radiation exposure while maintaining connectivity. Doing so requires incentives, transparency, and public pressure.

When in doubt, we must err on the side of caution. This means restrictingFootnote16 neonicotinoid use, especially in sensitive environments, and setting stricter guidelines for wireless radiation—particularly in schools and homes. It also means attentiveness to potential synergy between wireless radiation and chemical exposures leading to amplified adverse impacts on the productivity and stability of bee hives. These challenges cross borders, demanding international cooperation in science, regulation, and innovation.

Public education is essential. Informed citizens make better choices and demand better policies. The Environment webinar series aims to foster honest, inclusive dialogue about how we face today’s environmental crossroads—and how we find a better path forward.

At stake is more than academic debate. The decisions we make now will shape the future of our health, our ecosystems, and our shared planet. We can find our way—but only if we insist on transparency, independent science, democratic participation, and precaution in the face of uncertainty. Without them, we risk losing the trail entirely—at a cost we cannot afford.

Disclosure Statement

Devra Davis is treasurer of the Board of Directors of Environmental Health Trust, a nonprofit organization that voluntarily discloses sources of funding more than $5,000: https://ehtrust.org/about/. Stacy Malkan is managing editor of U.S. Right to Know, a nonprofit newsroom and public health research group that also voluntarily discloses sources of funding more than $5,000 at https://usrtk.org/donors/. Oladele A. Ogunseitan is unpaid co-chair of Apple Inc.’s Green Chemistry Advisory Board.

https://www.tandfonline.com/doi/full/10.1080/00139157.2025.2518032

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From particulates to pathways: environmental exposures and their impact on Alzheimer's disease

Liu B, Ahmad MA, Abbas G, Ahmed U, Javed R, Ali I, Ao Q, Deng X. From particulates to pathways: environmental exposures and their impact on Alzheimer's disease. Brain Res. 2025 Aug 8:149880. doi: 10.1016/j.brainres.2025.149880.

Abstract

Alzheimer's disease (AD) is a leading cause of cognitive decline and mortality, with its neurobiological mechanisms and etiology still not fully understood. Emerging evidence highlights the significant role of environmental pollutants in AD onset and progression. This review examines the impact of environmental compartments-air, water, soil, and pollutants-on AD pathology. Prolonged exposure to particulate matter (PM2.5), heavy metals (lead, cadmium, mercury, arsenic), and engineered nanomaterials (silver, iron oxide, silica) increases AD risk. Additional factors like obesity, smoking, infections, cardiovascular diseases, diabetes, and electromagnetic fields may exacerbate AD. These exposures potentially drive key pathological features such as amyloid-β plaque deposition and tau protein aggregation. By analyzing recent studies, this review highlights the intersection between environmental exposure and AD progression, emphasizing how such factors can accelerate the disease. It provides practical guidelines to mitigate these risks, aiming to reduce AD incidence while advancing understanding of its environmental contributions.

4.9. Electromagnetic fields

Electromagnetic fields (EMFs) are produced by various electronic devices, including those used in wireless communication, such as cell phones, Wi-Fi routers, and smart meters. EMFs are categorized into two main types: low-frequency (e.g., power lines) and high-frequency (e.g., radiofrequency radiation from wireless devices) (Meenu et al., 2024). The increasing prevalence of EMF exposure in daily life has raised concerns regarding its potential impact on brain health, particularly its role in neurodegenerative diseases such as AD (Jiang et al., 2016).

One of the central hypotheses regarding EMF exposure and AD is based on the calcium hypothesis of neurodegeneration. High-intensity EMFs are thought to interact with voltage-gated calcium channels in brain cells, which are responsible for regulating the influx of calcium ions (Ca2+) into neurons. Research suggests that the increased concentration of Ca2+ ions resulting from EMF exposure may contribute to a cascade of pathological processes associated with neurodegeneration, including excessive calcium signaling, oxidative stress, and inflammation (Pall, 2022). The dysregulation of calcium homeostasis is a well-established mechanism in AD, where elevated intracellular calcium levels can lead to neuronal damage, synaptic dysfunction, and ultimately cell death.

Animal studies have provided compelling evidence supporting the role of EMFs exposure in the accumulation of amyloid-β, a hallmark protein involved in AD. For example, a study involving rats exposed to daily pulsed EMFs demonstrated elevated levels of amyloid-β plaques in the brain, suggesting that EMFs exposure could accelerate amyloid pathology and contribute to cognitive decline (Li et al., 2019). The deposition of amyloid-β plaques is a critical event in the pathogenesis of AD, as these plaques disrupt neuronal communication and promote inflammation, thereby exacerbating neurodegeneration. In addition to amyloid-β accumulation, neurodegeneration itself is another key consequence of EMF exposure. Human studies have shown that prolonged exposure to EMFs may lead to widespread loss of dendritic spines and synaptic connections in the brain (Pritchard et al., 2019). Dendritic spines are small protrusions on neurons that play a critical role in synaptic signaling and cognitive processes. Their loss is a key feature of neurodegenerative diseases, including AD (Wyszkowska et al., 2019). Increased calcium ion influx resulting from EMF exposure may disrupt the structural integrity of dendritic spines, leading to synaptic dysfunction and cognitive impairment (Glaser et al., 2019, Popugaeva et al., 2017, Tong et al., 2018).

In a study by Tong et al., (2018), exposure to EMFs was found to increase calcium ion levels in neuronal cells, which led to the activation of signaling pathways associated with neuroinflammation and oxidative stress. These pathways are implicated in the progressive damage to neurons seen in AD and other neurodegenerative disorders. Additionally, chronic EMFs exposure has been shown to induce neuroinflammatory responses, which play a central role in the pathophysiology of AD. Inflammation in the brain, often triggered by the activation of microglial cells, can lead to the release of cytokines and other inflammatory mediators that further exacerbate neuronal damage and amyloid plaque accumulation (Kim et al., 2021). Another key aspect of the EMF-AD connection is the role of oxidative stress. Exposure to EMFs has been shown to increase the production of reactive oxygen species (ROS) in neurons, which can lead to oxidative damage to cellular components, including lipids, proteins, and DNA. This oxidative damage is thought to be a major contributor to the pathogenesis of Alzheimer's Disease, as it impairs neuronal function and accelerates the formation of amyloid plaques and tau tangles, both of which are characteristic of AD pathology (Bektas and Dasdag, 2025). Some studies have even suggested that individuals living in close proximity to sources of high-intensity EMF radiation, such as cell towers or power lines, may have an increased risk of developing neurodegenerative diseases, including Alzheimer's (Huss et al., 2009).

4.10. Synergistic effects of combined environmental pollutants

While much of the research on environmental risk factors for AD focuses on individual pollutants, growing evidence suggests that the combined effects of multiple exposures may significantly increase the risk of developing the disease (Wang et al., 2025). The synergistic interactions between various pollutants, such as smoking and heavy metals, can lead to more severe neuroinflammation, oxidative stress, and neuronal damage than the effects of any single exposure (Krisanova et al., 2024). For example, smoking and heavy metal exposure are two well-established risk factors for AD. Smoking leads to the generation of ROS and inflammation, which can directly damage neurons and alter amyloid-β processing (Wallin et al., 2017). When combined with exposure to heavy metals like cadmium, lead, or arsenic, the effects of smoking are often amplified. Heavy metals, by disrupting cellular homeostasis and enhancing oxidative stress, can exacerbate the damage caused by smoking. Specifically, cadmium has been shown to increase the permeability of the blood–brain barrier (BBB), allowing for easier access of amyloid-beta peptides into the brain, and promoting tau hyperphosphorylation (Ramírez-Mendoza et al., 2024). The combination of these pollutants leads to a vicious cycle of neuroinflammation, neuronal death, and cognitive decline, significantly increasing the risk of AD development in individuals who are exposed to both factors (Fu et al., 2022). The synergistic effects of combined exposures to environmental pollutants underscore the complexity of AD risk factors and highlight the need for more comprehensive studies that examine multifactorial exposures (Ahmed et al., 2025). Current research often focuses on individual risk factors in isolation, but the combined impact of pollutants is likely to provide a more accurate representation of real-world exposures (Aderinto et al., 2025b).

7. Conclusions

This monograph has underscored the critical impact of environmental risk factors stemming from industrialization, modern agriculture, and other pollutants on mental health, particularly in the context of AD. As AD research reaches a pivotal moment, the multifaceted role of environmental influences in the onset and progression of this disorder is becoming increasingly clear. Despite significant advances in understanding the pathobiology of AD, many aspects remain unresolved, particularly regarding the early causative events triggered by environmental pollutants, which continue to be elusive.

Biochemical analyses and both in vitro and in vivo studies have confirmed the role of amyloid-beta (Aβ) aggregation in initiating AD, but therapeutic strategies targeting amyloid have thus far proven ineffective. This highlights the urgent need for a deeper exploration of the mechanisms that link environmental exposures to AD onset. Additionally, the rise of NMs as emerging contributors to AD progression further emphasizes the complexity of environmental impacts on neurological health.

By addressing the limitations of current research and pursuing the outlined future directions, we can gain valuable insights into how environmental factors contribute to AD and how these risks can be mitigated. This research holds the potential to enhance our understanding of AD and guide the development of public health policies and interventions aimed at reducing the burden of this devastating disease.

https://pubmed.ncbi.nlm.nih.gov/40784621/

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Acoustic Pressures in the Head from Pulsed Microwaves: Can They Explain the Havana Syndrome?

Foster KR, Diao Y, Chou C-K. Acoustic Pressures in the Head from Pulsed Microwaves: Can They Explain the Havana Syndrome?. TechRxiv. August 12, 2025. doi: 10.36227/techrxiv.175502739.93949559/v1

Abstract

The microwave auditory effect-referring to "clicks" or "buzzing" sensations that a person experiences when their head is exposed to pulsed microwave energy such as emitted by radar transmitters, has been known since the 1960s. Formerly a threshold hearing phenomenon, the effect has gained renewed interest due to the advent of high powered microwave sources in recent decades. Does it represent a potential danger to people exposed to high powered microwave pulses?


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Panax ginseng Ameliorates Pituitary-ovarian Dysfunction Induced by Radiofrequency Electromagnetic Radiation from Cell Phones via Upregulation of the CREM Signaling Pathway

Oyewopo OA, Badejogbin OC, Ajadi IO, Enye LA, Ajadi MB, Ebuwa IV, Owolabi OV, Areloegbe SE, Olaniyi KS. Panax ginseng Ameliorates Pituitary-ovarian Dysfunction Induced by Radiofrequency Electromagnetic Radiation from Cell Phones via Upregulation of the CREM Signaling Pathway. Curr Drug Discov Technol. 2025;22(2):e300424229527. doi: 10.2174/0115701638279386240425050818. 

Abstract

Background: Panax ginseng (PG) is a plant that contains ginsenosides, which are considered adaptogens that confer cellular protection. However, the impact of PG on pituitary-ovarian dysfunction and subsequent infertility is unknown. This study investigated the hypothesis that PG would attenuate pituitary-ovarian dysfunction associated with mobile phone's Radiofrequency Electromagnetic Radiation (RF-EMR) in experimental rat models and the possible involvement of a cAMP Response Element Modulator (CREM)-dependent pathway.

Methods: Twenty adult female Wistar rats were divided randomly into four groups, each consisting of five rats. The control group was administered a vehicle (distilled water) orally, while the P. ginseng group received 200 mg/kg of P. ginseng extract orally. The RF-EMR group was exposed to 900MHz radiation, and the RF-EMR + PG group was exposed to the same radiation while also being treated with 200 mg/kg of P. ginseng orally. These treatments were administered daily for a period of 56 days.

Results: The RF-EMR group exhibited significant reductions in serum levels of LH, FSH, estradiol, and progesterone compared to the control group. Moreover, levels of superoxide dismutase (SOD) and glutathione peroxidase (GPx) were significantly lower in the RF-EMR group compared to the control. Additionally, there was a notable decrease in the expression of the CREM gene, accompanied by disrupted pituitary/ovarian morphology in the RF-EMR group compared to the control. However, the administration of PG mitigated these changes.

Conclusion: The findings of this study indicate that P. ginseng extract shields against pituitary-ovarian impairment linked to RF-EMR exposure from cell phones by boosting antioxidant capacity and promoting the CREM-dependent pathway.


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Impact of in vitro exposure to 5G-modulated 3.5 GHz fields on oxidative stress and DNA repair in skin cells  

Haidar J, Nabos P, Orlacchio R, et al. Impact of in vitro exposure to 5G-modulated 3.5 GHz fields on oxidative stress and DNA repair in skin cells. Sci Rep 15, 31214 (2025). https://doi.org/10.1038/s41598-025-15090-w.

Abstract

The rapid deployment of fifth-generation (5G) wireless networks has raised societal concerns regarding potential biological effects, particularly on human skin, due to the use of higher carrier frequencies that penetrate tissue less deeply. Consequently, whether 5G-modulated radiofrequency (RF) electromagnetic fields (EMFs) at 3.5 GHz affect oxidative stress and DNA repair in skin cells remains an open question. Using genetically encoded Bioluminescence Resonance Energy Transfer (BRET)-based biosensors targeted to the cytoplasm and mitochondria, we assessed whether exposure of human fibroblasts to 5G RF-EMF at specific absorption rates (SAR) of 0.08 and 4 W/kg for 24 h could alter basal reactive oxygen species (ROS) levels or potentiate the effects of known ROS inducers, including H₂O₂, Kp372-1, and Antimycin A. We also evaluated whether pre-exposure to 5G RF-EMF could induce an adaptive response (AR), by modulating ROS production following a subsequent challenge with arsenic trioxide (As₂O₃). Additionally, we investigated the impact of combined RF-EMF and ultraviolet-B (UV-B) exposure on the formation and repair of cyclobutane pyrimidine dimer (CPD) lesions in HaCaT keratinocytes. Our results showed no significant effect of 5G RF-EMF exposure, either alone or in combination with chemical ROS inducers, on oxidative stress markers in either compartment. Likewise, RF-EMF exposure did not induce an adaptive response to oxidative challenge, nor did it alter the kinetics or the efficiency of CPD repair by the nucleotide excision repair (NER) pathway. These findings support the conclusion that the exposure to 5G RF-EMF at 3.5 GHz up to 4 W/kg does not induce oxidative stress or impair DNA repair efficiency in human skin cells, within the experimental conditions tested.

Excerpt

In summary, our investigation—combining novel biosensing technology with robust experimental design—demonstrates that 5G-modulated 3.5 GHz RF-EMF does not affect oxidative stress levels, trigger adaptive response, or interfere with DNA repair processes in human skin cells at steady temperature. These results are consistent with current assessments by international experts and provide meaningful data for an evidence-based risk assessment of RF-EMF exposure in the context of 5G deployment. Nevertheless, it is important to note that our findings are based on acute in vitro exposure protocols lasting up to 24–48 h. While such durations are commonly used to assess direct cellular responses, they do not fully recapitulate the chronic or long-term exposures experienced in real-life settings. Therefore, future studies will be necessary to confirm these findings in more physiologically relevant models, including long-term or repeated exposures in 3D reconstructed skin or in vivo systems


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Dual Evaluation and Spatial Analysis of RF-EMF Exposure in 5G: Theoretical Extrapolations and Direct Measurements

Najera A, Villaescusa-Tebar A, Gonzalez-Rubio J, Garcia-Pardo C. Najera A, Villaescusa-Tebar A, Gonzalez-Rubio J, Garcia-Pardo C. Dual Evaluation and Spatial Analysis of RF-EMF Exposure in 5G: Theoretical Extrapolations and Direct Measurements. Bioelectromagnetics. 2025 Sep;46(6):e70020. doi: 10.1002/bem.70020. 

Abstract

This study evaluates radiofrequency electromagnetic field (RF-EMF) exposure in 5G networks using a dual approach that combines theoretical extrapolations and direct measurements in diverse semiurban and urban environments, specifically on the campus of the Polytechnic University of Valencia. Measurements were conducted using personal exposimeters under active traffic conditions on the 5G network, complemented by a code-selective measurement system based on an R&S TSME6 scanner. This approach enabled the calculation of maximum theoretical exposure by detailed analysis of 5G signals and the capture of key parameters such as cell ID and beam indices at 16 representative points across the campus. For precise spatial visualization, Kriging interpolation techniques in ArcGIS were employed to generate continuous exposure maps illustrating the spatial distribution of RF-EMF in the study area. The results indicate that both the extrapolated theoretical values and measured levels align with the limits recommended by the ICNIRP, even under high data demand scenarios, supporting current safety assessments of 5G infrastructure regarding electromagnetic exposure. The correlation between theoretical and instantaneous exposures validates the applied methodology and its effectiveness in assessing exposure in diverse environments. This study provides a robust framework for future research and highlights the importance of continuous monitoring to ensure public safety during the deployment of new telecommunications infrastructure in urban areas.


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Assessment of 5G RF-EMF Exposure during Large-Scale Public Events via Field Measurements

Villaescusa-Tebar A, Garcia-Pardo C. Assessment of 5G RF-EMF Exposure during Large-Scale Public Events via Field Measurements. IEEE Access, 2025. doi: 10.1109/ACCESS.2025.3602263.

Abstract

The development of Fifth-Generation (5G) mobile networks has raised public concern regarding human exposure to radiofrequency electromagnetic fields (RF-EMF). Key 5G features such as higher operating frequencies, broader bandwidths, beamforming, and traffic-dependent signal variability significantly influence RF-EMF exposure dynamics. Although many studies have assessed EMF levels induced by specific base stations under controlled user traffic, little empirical data are available on population-wide 5G environmental exposure across diverse scenarios. This study addresses this gap through field measurements conducted during a large public festival in Valencia, Spain and a baseline day prior to the event. Downlink signals from the 700 MHz and 3500 MHz 5G bands were measured across Spain’s three main network operators. Five locations surrounding the event venue were selected to capture the influence of the measurement location, and two measurement durations (6 and 30 min) were compared to assess temporal dynamics. The results showed that during the event, the power density in the 3500 MHz band increased by up to a factor of eight compared to the baseline conditions. However, even the highest recorded exposure levels remained well below the international safety limits. Additionally, a 30-minute continuous measurement revealed an approximately 30% increase in average power density compared to a 6-minute snapshot. These findings confirm that 5G environmental RF-EMF exposure remains within safe limits, even under high-demand conditions, and underscore the relevance of considering measurement location and temporal variability in exposure assessments.


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5G RF EMF Spectral Exposure Assessment in Four European Countries

Deprez K, Stroobandt B, Veludo AF, Vecsei Z, Necz PP, Politański P, Verloock L, Polanska K, Thuróczy G, Röösli M, Plets D, Joseph W. 5G RF EMF Spectral Exposure Assessment in Four European Countries. Bioelectromagnetics. 2025 Sep;46(6):e70019. doi: 10.1002/bem.70019. 

Abstract

This study assesses the exposure to 5G radio frequency electromagnetic fields (RF EMF) across four European countries. Spot measurements were conducted indoor and outdoor in both public spaces and educational institutions, encompassing urban and rural environments. In total, 146 measurements were performed in 2023, divided over Belgium (47), Switzerland (38), Hungary (30) and Poland (31). At 34.9% of all measurement locations a 5G connection to 3.6 GHz was established. The average cumulative incident power density (Savg) and maximum cumulative incident power density (Smax) were determined, for both “background” exposure (no 5G user equipment; No UE) and worst-case exposure (maximum downlink with 5G user equipment; Max DL). Furthermore, 3.6 GHz 5G-specific average Savg,5G and maximum Smax,5G incident power density are considered as well. For the No UE scenario, the highest Smax is 17.6 mW/m2, while for the Max DL, the highest Smax is 23.3 mW/m2. Both values are well within the ICNIRP guidelines. The highest Smax,5G measured over all countries and scenarios was 10.4 mW/m2, which is 3.2% of the frequency-specific ICNIRP guidelines. Additionally, a comparison was made between big cities, secondary cities, and villages for all four countries. The ratio of power density measured in rural areas was significantly lower than in urban areas (−4.8 to −10.4 dB). Under LOS conditions, the average incident power density was 2.3 mW/m2, whereas under NLOS conditions, the average incident power density decreases to 0.9 mW/m2. Furthermore, the relative variation increases under NLOS scenarios. Lastly, an analysis was performed regarding the power density in educational institutions compared to all other measurement locations, both indoors and outdoors for the different city types. The measured incident power density is not extensively lower in or around schools compared to public places, neither in the big cities, secondary cities, or the villages.

Summary

  • Radio frequency electromagnetic fields exposure assessment measurements across four European countries are conducted using a standardized measurement method.

  • All measurements were well within the ICNIRP guidelines.

  • The incident power density measured in rural areas was significantly lower than in urban areas.

Conclusion

The findings of this study provide a comparison of downlink RF EMF exposure from base stations for mobile telecommunications, presented in terms of spectral power density, across Belgium, Switzerland, Hungary, and Poland. First, a comparison was made of the RF EMF exposure regulations of all countries. While all countries follow similar RF EMF exposure regulations, Belgium and Switzerland have additional precautionary limits. In total, 146 measurement locations were assessed in 2023, divided over Belgium (47), Switzerland (38), Hungary (30) and Poland (31). 34.9% of all measurement locations had 5G coverage at 3.6 GHz, although there was a distinction between urban and rural areas in available 3.6 GHz 5G base stations. The study included both average and maximum cumulative incident power densities for two scenarios: “background” (No UE) and “worst-case” (Max DL) exposure. Furthermore, 3.6 GHz 5G-specific average and maximum incident power density (Savg,5G and Smax,5G) were included as well. The highest maximum cumulative power density for the No UE scenario was 17.6 mW/m2. For the Max DL scenario, the highest maximum cumulative power density was 23.3 mW/m2. These cumulative power densities, and by extension all measurements, remain well below 1, indicating compliance with ICNIRP guidelines. The highest 3.6 GHz 5G power density measured over all countries and scenarios was 10.4 mW/m2, which is 0.1% of the frequency-specific ICNIRP guidelines. The ratio of power density measured in rural areas was significantly lower than in urban areas (−4.8 to −10.4 dB), for all countries over the two scenarios, as expected due to less nearby base stations and generally less users.

A comparison between LOS and NLOS measurement locations is made. Under LOS conditions, the average incident power density was 2.3 mW/m2, whereas under NLOS conditions, the average incident power density decreases to 0.9 mW/m2. Furthermore, the relative variation increases under NLOS scenarios. Lastly, an analysis was performed regarding the power density in educational institutions compared to all other measurement locations, both indoors and outdoors for the different city types. The measured incident power density is not extensively lower in or around schools compared to public places, in neither the big cities, secondary cities or the villages. The RF EMF exposure levels in all measured environments were well below the ICNIRP guidelines.

For future work, increasing the number of measurements and regularly reassessing exposure levels will be essential to monitor the continued rollout of 5G networks and related exposure trends. Therefore, these measurements will be repeated in 2025. Furthermore, the different measurement methods within GOLIAT will be combined to achieve an even better understanding regarding RF EMF exposure.

Open access: https://onlinelibrary.wiley.com/doi/10.1002/bem.70019

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Assessment of spatial-average absorbed power density and peak temperature rise in skin model under localized electromagnetic exposure 

Zheng J, Zhang Y, Diao Y, Shi D. Assessment of spatial-average absorbed power density and peak temperature rise in skin model under localized electromagnetic exposure. Radiat Prot Dosimetry. 2025 Aug 16:ncaf096. doi: 10.1093/rpd/ncaf096.

Abstract

Numerical dosimetry for assessments of the absorbed power density (APD) and temperature rise has been conducted using multi-layer skin models, incorporating skin, fat, muscle, and other components, providing a scientific foundation for setting exposure limits. However, the influence of the vasculature on dosimetry outcomes remains underexplored. In this study, we developed a synthetic blood vessel model and integrated it into multi-layer skin models. Electromagnetic computations were performed, followed by steady-state temperature rise evaluations using the Pennes bioheat transfer equation across a frequency range of 3 to 30 GHz. To quantify the effect of vascular modeling on dosimetry results, simulations incorporating vasculature with varying endpoint diameters were compared to those without vasculature. Results showed that the effect of vascular modeling on peak spatial-averaged APD was negligible, and its influence on peak temperature rise was ~8% at 3 GHz, decreasing to less than <3% above 6 GHz. And the effect of the endpoint diameter is marginal. These variations are smaller than those previously reported due to changes in tissue thickness and dielectric or thermal properties. While the effect on peak temperature rise is modest, including vasculature helps refine localized thermal distributions and may inform future improvements in anatomical modeling. 


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Traceable Assessment of the Absorbed Power Density of Body Mounted Devices at Frequencies Above 10 GHz

Chitnis N, Karimi F, Kühn S, Fallahi A, Christ A, Kuster N. Traceable Assessment of the Absorbed Power Density of Body Mounted Devices at Frequencies Above 10 GHz. Bioelectromagnetics. 2025 Sep;46(6):e70018. doi: 10.1002/bem.70018.

Abstract

In this study, a comprehensive approach for the experimental assessment of the absorbed power density (APD) is developed. The method includes several novel components: (i) a specialized probe, (ii) a composite phantom, (iii) a reconstruction technique, (iv) a calibration method, and (v) a validation process. The described solution has been developed for the frequency range from 24 to 30 GHz, but can be extended to all frequency bands between 10 and 45 GHz. A novel composite phantom emulates the reflection and transmission coefficients of human skin for propagating and evanescent modes, while its increased penetration depth, in comparison to dermis tissue, enables the measurement of the induced electromagnetic fields (EMFs) with a new miniaturized dosimetric broadband probe. The implementation has a wide dynamic range and sufficient spatial resolution to use it for type approval of mobile devices. Its probe is calibrated with low uncertainty in a novel, traceable setup. A set of reference antennas with known numerical target values for the APD has been compiled to validate the measurement system. The validation demonstrates that the deviation is within the expanded uncertainty of 1.6 dB for pAPD and 1.5 dB for psAPD.

Summary

  • First traceable, broadband absorbed power density (APD) assessment method and procedures covering 10–45 GHz with a validated implementation for 24–30 GHz, having low uncertainty of < 1.6 dB for peak APD and < 1.5 dB for peak spatial-averaged APD (psAPD), enabling type approval of wireless devices.

  • Composite phantom design that emulates reflection and APD of skin across propagating and evanescent modes.

  • Reference-antenna-based validation that is instrumentation agnostic and covers realistic spatial gradients, spectral domain (k-space), and modulated signals in conformance with standard requirements for product test system qualification.

Open access: https://onlinelibrary.wiley.com/doi/10.1002/bem.70018

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Assessing exposure from different vehicular antennas in military applications: a computational study

Micol C, Biscarini M, Ferrante D, Pellegrino G, De Meis M, Mei L, Cavagnaro M, Apollonio F, Liberti M. Assessing exposure from different vehicular antennas in military applications: a computational study. Frontiers in Public Health. Volume 13 - 2025. doi: 10.3389/fpubh.2025.1620240.

Abstract

Introduction  Military personnel frequently operate in close proximity to electromagnetic (EM) sources such as vehicular communication antennas. Despite this occurrence, detailed evaluations of exposure scenarios remain limited. This study bridges this gap by examining EM exposure from military vehicular antennas, covering a broad spectrum of frequencies (high frequency—HF, very high frequency—VHF, ultrahigh frequency—UHF), power levels, and positions.

Methods  The study used computational modeling to simulate realistic military scenarios, including personnel partially outside armored vehicles and equipped with personal protective equipment. Simulations accounted for a broad spectrum of frequencies (HF, VHF, and UHF) as well as different power levels, antenna types and locations.

Results  The analysis revealed substantial variability in EM exposure levels depending on the configuration and conditions. While all simulated scenarios complied with the ICNIRP Basic Restrictions (BR), certain cases exceeded the Reference Levels (RL), particularly under specific positioning and frequency combinations.

Conclusions  These findings, based on a detailed case-specific analysis, suggest that personnel safety in military contexts is generally maintained, even in the presence of variable exposure conditions and elevated levels of radiated E-field. Considering the basic structure of the radiating source (i.e., monopole) and the nature of near-field interactions, this paper suggests that safe exposure conditions could be expected to persist across a range of antenna-operator positioning configurations, and building on previous preliminary research on this topic, it provides relevant insights for operational instructions and improving safety regulations in the military field.


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In situ electric field dosimetry analysis for powerline frequency peripheral nerve magnetic stimulation

Fresnel E, Bouisset N, Soyka F, et al. In situ electric field dosimetry analysis for powerline frequency peripheral nerve magnetic stimulation. Sci Rep 15, 29887 (2025). https://doi.org/10.1038/s41598-025-12284-0.

Abstract

Humans are exposed to environmental 60 Hz magnetic fields (MFs), inducing in our body electric fields (EFs) and currents, potentially stimulating the peripheral nervous system (PNS). Uncertainties exist regarding the 60 Hz MF PNS stimulation threshold. The spatially extended nonlinear node model (SENN) is used to help define international MF exposure guidelines and standards protecting workers and the general public. However, other models exist, particularly the McIntyre–Richardson–Grill (MRG) model, the new gold standard for electrostimulation. This study aims (1) to model a new extremely low frequency MF exposure system for the human leg and (2) to investigate the in situ EFs generated by the system at 60 Hz at the skin level and in the nerves of the leg using a realistic human body model with both the SENN and the MRG models. A Helmholtz like-coil system was designed to generate in situ EFs sufficient for nerve stimulation, modeled using Biot–Savart and Faraday laws. Sim4Life simulations assessed the induced EFs at skin and nerve levels using a detailed human body model and two nerve excitation frameworks: the SENN and MRG models. High EF intensities were observed in four sensory and sensory-motor nerves, with MRG-derived thresholds lower than SENN-derived thresholds. Results also highlight the significance of nerve orientation in EF induction. This study emphasizes the critical role of comprehensive modeling for the design and validation of MF exposure systems and underscores the need for experimental data to refine models, standards, and guidelines.


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Instruments and Measurement Techniques to Assess Extremely Low-Frequency Electromagnetic Fields

Rathebe PC, Kholopo M. Instruments and Measurement Techniques to Assess Extremely Low-Frequency Electromagnetic Fields. Sensors (Basel). 2025 Aug 7;25(15):4866. doi: 10.3390/s25154866.

Abstract

This study presents a comprehensive evaluation and selection framework for extremely low-frequency electromagnetic field (ELF-EMF) measurement instruments. Recognizing the diversity of application environments and technical constraints, the framework addresses the challenges of selecting appropriate tools for specific scenarios. It integrates a structured, quantitative approach through a weighted scoring matrix that evaluates instrumentation across six criteria: monitoring duration, sensitivity, environmental adaptability, biological/regulatory relevance, usability, and cost. Complementing this is a logic-based flowchart that visually guides decision-making based on user-defined operational needs. The framework is applied to a realistic occupational case study, demonstrating its effectiveness in producing evidence-based, scenario-sensitive instrument recommendations. This method provides stakeholders with a transparent and adaptable tool for ELF-EMF device selection.


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Weak anthropogenic electric fields affect honeybee foraging

Mallinson VJ. Woodburn FA, O’Reilly KJ. Weak anthropogenic electric fields affect honeybee foraging. Cell Press. 2025. https://doi.org/10.1016/j.isci.2025.112550.

Highlights

• Weak anthropogenic-like electric fields reduce honeybee floral landing
• AC and positive DC fields deter honeybee landing, but negative DC does not
• Electric fields near power lines match experimental levels, spanning tens of meters
• These findings highlight electric pollution as a potential disruptor of pollination

Summary

Aerial electroreception, the detection of airborne electric fields (E-fields), is an emerging sensory system in arthropods, including bees, which can use floral E-fields as foraging cues. However, the influence of anthropogenic E-fields on these interactions remains underexplored. Through field experiments in urban meadows, we demonstrate that weak anthropogenic E-fields, including alternating current (AC) and direct current (DC) fields, significantly alter honeybee floral landing behaviors. AC and positive DC fields reduced landings by 71% and 53%, respectively, whereas negative DC fields had no statistically significant impact. Measurements of E-fields near high-voltage transmission lines revealed persistent field strengths comparable to those used experimentally, spanning tens of meters at heights relevant for bee foraging. These findings underscore the potential for anthropogenic E-fields to affect and potentially disrupt plant-pollinator interactions, threatening pollination efficiency, a cornerstone of agriculture and biodiversity. Our study highlights the need for advancing research on the ecological impacts of electric pollution.


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Combined effects of constant temperature and radio frequency exposure on Aedes mosquito development

Dom NC, Dapari R, Halim NMHNA, Rahman ATA. Combined effects of constant temperature and radio frequency exposure on Aedes mosquito development. Sci Rep. 2025 Aug 20;15(1):30571. doi: 10.1038/s41598-025-09383-3. 

Abstract

Mosquito-borne diseases, such as dengue, Zika, and chikungunya, pose significant public health threats, particularly in tropical regions like Malaysia. Aedes aegypti and Aedes albopictus are primary vectors of these diseases, with their developmental stages being highly sensitive to environmental factors. While temperature is a well-known driver of mosquito biology, the potential influence of anthropogenic factors such as radio frequency (RF) exposure remains underexplored. This study investigates the combined effects of temperature and RF exposure on the developmental stages of these mosquito species to provide insights into their population dynamics and inform vector control strategies. A factorial experimental design was employed, incorporating four temperature conditions (20 °C, 25 °C, 30 °C, and 35 °C) and three RF exposure levels (900 MHz, 18 GHz, and a control group with no RF exposure). The developmental durations for hatching, larval, pupation, and adult emergence stages were monitored daily under controlled laboratory conditions. Data were analyzed using a quadratic response surface model to evaluate the main effects and interactions between temperature and RF exposure. Temperature emerged as the dominant factor influencing developmental durations, with optimal conditions observed at 30-32 °C. RF exposure, particularly at 18 GHz, acted as a secondary modulating factor, accelerating developmental stages under certain temperature conditions. Ae. aegypti exhibited greater sensitivity to temperature changes compared to Ae. albopictus, which displayed higher adaptability and resilience to environmental variations. Interaction effects were most evident at intermediate temperatures (25-30 °C), where RF exposure synergistically reduced developmental durations. However, extreme RF exposure levels and suboptimal temperatures prolonged developmental periods. This study highlights the critical role of temperature in mosquito development while identifying RF exposure as a potential modulator under specific conditions. The findings underscore the importance of considering both environmental and anthropogenic factors in vector management strategies. Future research should explore the molecular mechanisms underlying these interactions to refine predictive models and enhance vector control efforts in rapidly urbanizing regions.

Conclusion

In summary, temperature is the primary determinant of mosquito developmental durations, with RF exposure exerting secondary modulating effects under specific conditions. Ae. aegypti was more sensitive to environmental variations, while Ae. albopictus displayed greater resilience and adaptability. These findings provide a foundation for incorporating environmental variables, including anthropogenic factors such as RF exposure, into predictive models for mosquito population dynamics and vector management. Future research should explore the molecular mechanisms underlying these interactions and assess their implications for disease transmission and control in different ecological settings.


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Effect of Static Electromagnetic Field on Growth Parameters, Survival Rate, Sex Distribution, Ratio, and Liver and Gonadal Health of Zebrafish

Çek Ş, Ünal E, Doğan EA, Yaraş KU, Dede K, Karaaslan M. Effect of Electromagnetic Field on Growth Parameters, Survival Rate, Sex Distribution, Ratio, and Liver and Gonadal Health of Zebrafish (Danio rerio). Bull Environ Contam Toxicol. 2025 Aug 25;115(3):33. doi: 10.1007/s00128-025-04103-z. PMID: 40855214.

Abstract

This study examines the impact of electromagnetic fields (EMF) on zebrafish (Danio rerio) sex ratio, survival, and organ health. Embryos were exposed to static EMFs for 63 days post-hatching across five aquariums, with varying intensities based on distance (30-99 cm). The control group remained EMF-free. The strongest exposure (30 cm) led to 100% feminization (p < 0.001), with all exposed groups showing significant deviations from the expected 1:1 sex ratio. Survival rates dropped below 35% in EMF-exposed groups, compared to 82.5% in controls. Histological analysis revealed gonadal abnormalities, necrosis, and liver degeneration in exposed fish. These findings provide the first documented evidence that EMF exposure disrupts sex ratios and health in fish, potentially affecting population stability in aquatic ecosystems. The predominance of females suggests long-term ecological consequences that could impact biodiversity in both aquatic and terrestrial environments.



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Exposure of human lymphocytes to sweeping-frequency extremely low frequency magnetic field

Zastko L, Makinistian L, Petrovičová P, Tvarožná A, Belyaev I. Exposure of human lymphocytes to sweeping-frequency ELF MF. Int J Radiat Biol. 2025 Aug 7:1-10. doi: 10.1080/09553002.2025.2542322.

Abstract

Purpose  Whereas most of the research on possible bioeffects of extremely low frequency magnetic fields (ELF MF) on blood cells has been performed at 50/60 Hz regardless of background fields, here, we exposed human lymphocytes to sweeping-frequency ELF MF in a different range, defined by the DC background field of our incubator and the corresponding ion-cyclotron frequencies.

Materials and methods  Umbilical cord blood lymphocytes (UCBL) were isolated and exposed for 48 h to an ELF MF (sinusoidal, frequency sweeping 3–26 Hz) with 6 different amplitudes between 6 µT and 24 µT, utilizing an oblong coil. DNA double-strand breaks (DSB) were assessed by enumeration of γH2AX, 53BP1 and γH2AX/53BP1 co-localized DNA repair foci. Percentage of viable, early apoptotic (EA), and late apoptotic/necrotic (LAN) cells were determined.

Results  No statistically significant effects were seen for DNA repair foci or apoptosis induction after a 48-h exposure of UCBL with frequency-sweeping ELF MF. More than 2-fold decrease (p = .064) of γH2AX foci level was detected for 8 µT amplitude when compared to controls. For the same field intensity, a decrease in viable cells was suggested by the data.

Conclusions  Our findings suggest that at least part of the exposure could have had a preventive/blocking effect on DNA DSB formation suggesting the possibility of using sweeping-frequency ELF MF as a protective measure against genotoxic agents. It is desirable to continue testing variations of the exposure utilized in this work, in order to search for the most biologically effective frequencies/patterns of exposure.


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Magnetic effects in biology: Crucial role of quantum coherence in the radical pair mechanism

Binhi V.  Magnetic effects in biology: Crucial role of quantum coherence in the radical pair mechanism. Phys. Rev. E. 112, 014409. 25 July, 2025. doi: 1103/n3fs-fsnv.

Abstract

The spin-chemical radical pair mechanism (RPM) has emerged as a leading theory for explaining the biological effects of low-intensity magnetic fields. These intriguing effects occur when the quantum system of radicals is well isolated from the disturbing influence of the environment. In other words, these effects are closely related to the spin coherence relaxation time , but an explicit relationship has not yet been established. In our study, we found an analytical solution to the Liouville-Neumann equation for an open system made up of two electrons and one nucleus, considering minimal interactions while concentrating on spin relaxation and chemical kinetics. This solution, supported by numerical integration, highlights the crucial role of quantum coherence. A straightforward expression is proposed that describes the RPM effect as a function of , within the ranges of magnetic field strength and rate of chemical kinetics relevant to magnetobiology. Our findings reveal that RPM effects become significant only when fundamental relation holds: it controls the magnitude of the effects, and it is consistent with the principles of spin chemistry. Additionally, by comparing our results with existing experimental data, we estimate that the plausible spin decoherence times in magnetosensitive radical pairs within cryptochromelike proteins range from units to tens of nanoseconds. The effects of radio-frequency magnetic fields at the nT level were also examined, taking into account decoherence. These effects turned out to be negligible and incapable of disrupting the RPM patterns. The role of the quantum Zeno effect in magnetobiology is inspected from the perspective of the dependence of the RPM effect.

https://journals.aps.org/pre/abstract/10.1103/n3fs-fsnv